Typical Testing Data/Standard Curve (for reference only)
Rat Ectonucleoside triphosphate diphosphohydrolase 1 ELISA Kit | Entpd1 elisa kit
Rat Ectonucleoside triphosphate diphosphohydrolase 1 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
has apyrase activity; may inactivate signaling mediated by extracellular nucleotides [RGD, Feb 2006]
Uniprot Description
ENTPD1: an ectonucleotidase that, like CD73, hydrolyzes immunostimulatory ATP, and ADP, to immunosuppressive AMP. May inhibit host immune responses against cancer. Expressed at high levels in malignant epithelial cells of human rectal adenocarcinoma. A prognostic marker of chronic lymphocytic leukemia that may identify patients with an unfavorable clinical outcome. Synergizes with CD161 to modulate Th17 responses in Crohn's disease. It may hydrolyze ATP and other nucleotides in the nervous system to regulate purinergic neurotransmission in the nervous system. May be implicated in inhibiting platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. Belongs to the GDA1/CD39 NTPase family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Hydrolase; Membrane protein, multi-pass; Nucleotide Metabolism - pyrimidine; Nucleotide Metabolism - purine; Extracellular matrix; EC 3.6.1.5; Membrane protein, integral
Cellular Component: basal lamina; basolateral plasma membrane; cell soma; cell surface; extracellular space; integral to membrane; membrane; neuron projection; postsynaptic density; synaptic vesicle
Molecular Function: adenosine-diphosphatase activity; ATP binding; ATPase activity; hydrolase activity; identical protein binding; nucleoside-diphosphatase activity; nucleoside-triphosphatase activity
Biological Process: G-protein coupled receptor protein signaling pathway; negative regulation of dopamine secretion; platelet activation; protein homooligomerization; purine ribonucleoside diphosphate catabolic process; response to ATP; response to caffeine; response to gamma radiation; response to lipopolysaccharide; response to morphine; response to proline
Research Articles on Entpd1
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Product Notes
The Rat Entpd1 entpd1 (Catalog #AAA2883292) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2883292 ELISA Kit recognizes Rat Entpd1. It is sometimes possible for the material contained within the vial of "Ectonucleoside triphosphate diphosphohydrolase 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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