Human egf-like module containing, mucin-like, hormone receptor-like 3 ELISA Kit | EMR3 elisa kit

Human EGF-like module-containing mucin-like hormone receptor-like 3, EMR3 ELISA Kit

Cat. Num. AAA9325345

• Reactivity: Human
• Synonyms: egf-like module containing; mucin-like; hormone receptor-like 3; Human EGF-like module-containing mucin-like hormone receptor-like 3; EMR3 ELISA Kit; Human EGF-like module-containing mucin-like hormone receptor-like 3 (EMR3) ELISA kit; egf-like module-containing mucin-like receptor 3; EMR3 elisa kit

• Reactivity: Human

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 574584843
• NCBI GeneID: 84658
• NCBI Accession #: NP_001276087.1
• NCBI GenBank Nucleotide #: NM_001289158.1
• UniProt Accession #: Q9BY15
• Molecular Weight: 72,621 Da
• NCBI Official Full Name: EGF-like module-containing mucin-like hormone receptor-like 3 isoform 2
• NCBI Official Synonym Full Names: egf-like module containing, mucin-like, hormone receptor-like 3
• NCBI Official Symbol: EMR3
• NCBI Protein Information: EGF-like module-containing mucin-like hormone receptor-like 3; EGF-like module receptor 3; egf-like module-containing mucin-like receptor 3
• UniProt Protein Name: EGF-like module-containing mucin-like hormone receptor-like 3
• UniProt Gene Name: EMR3
• UniProt Synonym Gene Names: UNQ683/PRO1562
• UniProt Entry Name: EMR3_HUMAN

NCBI Description

This gene encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2014]

Uniprot Description

EMR3: Receptor probably involved in myeloid interactions during immune and inflammatory responses. A ligand for the soluble form of this receptor is present at the surface of momocytes- derived macrophages and activated neutrophils. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: GPCR, family 2; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 19p13.1

Cellular Component: extracellular space; plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; calcium ion binding

Biological Process: G-protein coupled receptor protein signaling pathway