Typical Testing Data/Standard Curve (for reference only)
hsp65 elisa kit
Hsp65 StressXpress ELISA Kit
Reactivity
Mycobacterium Bovis Hsp65;Mycobacterium Tuberculosum Hsp65
Synonyms
HSP65; Hsp65 StressXpress ELISA Kit; 60kDa chaperonin 2; Antigen A; Cell wall protein A; groEL; GroEL2; GroL2; M. Tuberculosis cell wall protein A; M. Tuberculosis Hsp65; Protein Cpm60 2; Hsp65 ELISA; Enzyme-Linked Immunosorbent Assay; hsp65 elisa kit
Reactivity
Mycobacterium Bovis Hsp65;Mycobacterium Tuberculosum Hsp65
Specificity
This assay is specific for Hsp65. The Hsp65 ELISA has been validated for the detection of Hsp65.
Sequence Length
133
Detection Range
0.344-22 ng/mL
Sensitivity
0.06 ng/mL
Preparation and Storage
4 degree C
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for hsp65 elisa kit
Background/Introduction: Hsp65 isolated from Mycobacterium bovis BCG, is a member of the hsp60 family of heat shock proteins (2,3). Hsp60s are mitochondrial chaperonins that are typically held responsible for the transportation and refolding of proteins from the cytoplasm into the mitochondrial matrix. In addition to its role as a heat shock protein, Hsp60 functions as a chaperonin to assist in folding linear amino acid chains into their respective threedimensional structure. Hsp60s are a ubiquitous class of HSPs that specifically promote the folding and assembly of cellular polypeptides in an ATP-dependent manner (1).Specifically, sequence comparison of Hsp65 from different mycobacterium strains showed that the protein sequence of M. bovis BCG is identical to that of M. tuberculosis, and very similar to that of M. leprae, the pathogens that cause tuberculosis and tuberculoid leprosy, respectively (2,4). Mycobacterium bovis BCG Hsp65 was identified as the immunodominant antigen during mycobacterial diseases and vaccination. It is also believed to be the antigen that induces autoimmune disease, such as adjuvant arthritis in rats (5, 6).
Product Categories/Family for hsp65 elisa kit
References
1. Koll H., et al. (1992) Cell. 68: 1163-1175. 2. HThole J.E.R., et al. (1985) Infect. Immuno. 50: 800-806. 3. Thole J.E.R., et al. (1987) Infect. Immuno. 55: 1466-1475. 4. hinnick T.M. Sweetser D., Thole J., van Embden J., Young R.A. (1987) Infect. Immuno.55: 1932-1935. 5. Van Eden W., et al. (1988) Nature 331: 171-178. 6. Cobelens P.M., et al. (2002) Rheumatology 41: 775-779.
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
13,795 Da
NCBI Official Full Name
Hsp65, partial
UniProt Protein Name
65 kDa heat shock protein
UniProt Gene Name
hsp65
UniProt Entry Name
B2D1C7_9MYCO
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Product Notes
The Mycobacterium Bovis Hsp65;Mycobacterium Tuberculosum Hsp65 HSP65 hsp65 (Catalog #AAA806870) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA806870 ELISA Kit recognizes Mycobacterium Bovis Hsp65;Mycobacterium Tuberculosum Hsp65 HSP65. It is sometimes possible for the material contained within the vial of "HSP65, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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