Mouse eukaryotic translation initiation factor 2C, 1 ELISA Kit | EIF2C1 elisa kit
Mouse Protein argonaute-1, EIF2C1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
AGO1: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for transcriptional gene silencing (TGS) of promoter regions which are complementary to bound short antigene RNAs (agRNAs). Interacts with DDB1, DDX5, DDX6, DHX30, DHX36, DDX47, DICER1, EIF2C2/AGO2, ELAVL1, HNRNPF, IGF2BP1, ILF3, IMP8, MATR3, MOV10, PABPC1, PRMT5, RBM4, SART3, TNRC6B, UPF1 and YBX1. Associates with polysomes and messenger ribonucleoproteins (mNRPs). Interacts with LIMD1, WTIP and AJUBA. Belongs to the argonaute family. Ago subfamily.
Protein type: Translation; RNA-binding
Cellular Component: polysome; cytoplasm; nucleus; ribonucleoprotein complex; cytosol
Molecular Function: protein binding; miRNA binding; nucleic acid binding; RNA binding
Biological Process: regulation of translation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; miRNA-mediated gene silencing, negative regulation of translation; positive regulation of transcription from RNA polymerase II promoter; RNA-mediated gene silencing
Research Articles on EIF2C1
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Product Notes
The Mouse EIF2C1 ago1 (Catalog #AAA9340198) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9340198 ELISA Kit recognizes Mouse EIF2C1. It is sometimes possible for the material contained within the vial of "eukaryotic translation initiation factor 2C, 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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