Testing Data
ECE1 recombinant protein
Human CellExp ECE1, Human Recombinant
Gene Names
ECE1; ECE
Purity
>95% by SDS-PAGE
Synonyms
ECE1; Human CellExp ECE1; Human Recombinant; Endothelin-converting enzyme 1; ECE-1; ECE1 recombinant protein
Host
HEK293 cells
Purity/Purification
>95% by SDS-PAGE
Form/Format
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4
Sequence
HHHHHHHHQYQTRSPSVCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLENSTASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYPVEINESEPIVVYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW
Gene Source
Human
Reconstitution Instruction
Reconstitute the lyophilized protein in ddH2O
Preparation and Storage
Store at -20 degree C
Centrifuge the vial prior to opening.
Shelf life: ~12 months
Centrifuge the vial prior to opening.
Shelf life: ~12 months
Testing Data
Testing Data
Testing Data
Testing Data
Related Product Information for ECE1 recombinant protein
Endothelin-Converting Enzyme-1 (ECE-1) is a single-pass type II transmembrane (TM) protein with a short cytoplasmic tail and a large ectodomain. ECE-1 is a zinc protease of the neprilysin (NEP) family, which also includes ECE-2, PEX, XCE, DINE, and Kell, and several NEP-like proteins. It is widely expressed and has several alternatively spliced forms that differ in their TM domain or cytoplasmic tail. All isoforms of ECE-1 are expressed in umbilical vein endothelial cells, polynuclear neutrophils, fibroblasts, atrium cardiomyocytes and ventricles. Endothelin-converting enzyme-1 is involved in the proteolytic processing of Endothelin-1 (EDN1), Endothelin-2 (EDN2), and Endothelin-3 (EDN3) to biologically active peptides. Defects in ECE1 are a cause of Hirschsprung disease, cardiac defects and autonomic dysfunction (HSCRCDAD). It is a form of Hirschsprung disease with skip-lesions defects, craniofacial abnormalities and other dysmorphic features, and autonomic dysfunction.
Product Categories/Family for ECE1 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
770
NCBI Official Full Name
endothelin-converting enzyme 1 isoform 3
NCBI Official Synonym Full Names
endothelin converting enzyme 1
NCBI Official Symbol
ECE1
NCBI Official Synonym Symbols
ECE
NCBI Protein Information
endothelin-converting enzyme 1; ECE-1
UniProt Protein Name
Endothelin-converting enzyme 1
Protein Family
UniProt Gene Name
ECE1
UniProt Synonym Gene Names
ECE-1
UniProt Entry Name
ECE1_HUMAN
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Product Notes
The ECE1 ece1 (Catalog #AAA849854) is a Recombinant Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: HHHHHHHHQY QTRSPSVCLS EACVSVTSSI LSSMDPTVDP CHDFFSYACG GWIKANPVPD GHSRWGTFSN LWEHNQAIIK HLLENSTASV SEAERKAQVY YRACMNETRI EELRAKPLME LIERLGGWNI TGPWAKDNFQ DTLQVVTAHY RTSPFFSVYV SADSKNSNSN VIQVDQSGLG LPSRDYYLNK TENEKVLTGY LNYMVQLGKL LGGGDEEAIR PQMQQILDFE TALANITIPQ EKRRDEELIY HKVTAAELQT LAPAINWLPF LNTIFYPVEI NESEPIVVYD KEYLEQISTL INTTDRCLLN NYMIWNLVRK TSSFLDQRFQ DADEKFMEVM YGTKKTCLPR WKFCVSDTEN NLGFALGPMF VKATFAEDSK SIATEIILEI KKAFEESLST LKWMDEETRK SAKEKADAIY NMIGYPNFIM DPKELDKVFN DYTAVPDLYF ENAMRFFNFS WRVTADQLRK APNRDQWSMT PPMVNAYYSP TKNEIVFPAG ILQAPFYTRS SPKALNFGGI GVVVGHELTH AFDDQGREYD KDGNLRPWWK NSSVEAFKRQ TECMVEQYSN YSVNGEPVNG RHTLGENIAD NGGLKAAYRA YQNWVKKNGA EHSLPTLGLT NNQLFFLGFA QVWCSVRTPE SSHEGLITDP HSPSRFRVIG SLSNSKEFSE HFRCPPGSPM NPPHKCEVW. It is sometimes possible for the material contained within the vial of "ECE1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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