Epstein-Barr nuclear antigen 1 (EBNA1), partial Recombinant Protein | EBNA1 recombinant protein
Recombinant Epstein-Barr virus Epstein-Barr nuclear antigen 1 (EBNA1), partial
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Epstein-Barr nuclear antigen 1 (EBNA1); partial; Recombinant Epstein-Barr virus Epstein-Barr nuclear antigen 1 (EBNA1); Epstein-Barr nuclear antigen 1; EBNA-1; EBV nuclear antigen 1; EBNA1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
458-641. Partial
Sequence
RRKKGGWFGKHRGQGGSNPKFENIAEGLRALLARSHVERTTDEGTWVAGVFVYGGSKTSLYNLRRGTALAIPQCRLTPLSRLPFGMAPGPGPQPGPLRESIVCYFMVFLQTHIFAEVLKDAIKDLVMTKPAPTCNIRVTVCSFDDGVDLPPWFPPMVEGAAAEGDDGDDGDEGGDGDEGEEGQE
Species
Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for EBNA1 recombinant protein
Plays an essential role in replication and partitioning of viral genomic DNA during latent viral infection. During this phase, the circular double-stranded viral DNA undergoes replication once per cell cycle and is efficiently partitioned to the daughter cells. EBNA1 activates the initiation of viral DNA replication through binding to specific sites in the viral latent origin of replication, oriP. Additionally, it governs the segregation of viral episomes by mediating their attachment to host cell metaphase chromosomes. Also activates the transcription of several viral latency genes. Finally, it can counteract the stabilization of host p53/TP53 by host USP7, thereby decreasing apoptosis and increasing host cell survival.
Product Categories/Family for EBNA1 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
35.8 kDa
NCBI Official Full Name
EBNA-1 protein
NCBI Official Symbol
BKRF1
NCBI Protein Information
EBNA-1 protein
UniProt Protein Name
Epstein-Barr nuclear antigen 1
Protein Family
UniProt Gene Name
EBNA1
UniProt Synonym Gene Names
EBNA-1; EBV nuclear antigen 1
UniProt Entry Name
EBNA1_EBVB9
Uniprot Description
Plays an essential role in replication and partitioning of viral genomic DNA during latent viral infection. During this phase, the circular double-stranded viral DNA undergoes replication once per cell cycle and is efficiently partitioned to the daughter cells. EBNA1 activates the initiation of viral DNA replication through binding to specific sites in the viral latent origin of replication, oriP. Additionally, it governs the segregation of viral episomes by mediating their attachment to host cell metaphase chromosomes. Also activates the transcription of several viral latency genes. Finally, it can counteract the stabilization of host p53/TP53 by host USP7, thereby decreasing apoptosis and increasing host cell survival.
Research Articles on EBNA1
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Product Notes
The EBNA1 ebna1 (Catalog #AAA1030632) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 458-641. Partial. The amino acid sequence is listed below: RRKKGGWFGK HRGQGGSNPK FENIAEGLRA LLARSHVERT TDEGTWVAGV FVYGGSKTSL YNLRRGTALA IPQCRLTPLS RLPFGMAPGP GPQPGPLRES IVCYFMVFLQ THIFAEVLKD AIKDLVMTKP APTCNIRVTV CSFDDGVDLP PWFPPMVEGA AAEGDDGDDG DEGGDGDEGE EGQE . It is sometimes possible for the material contained within the vial of "Epstein-Barr nuclear antigen 1 (EBNA1), partial, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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