F-box-like/WD repeat-containing protein ebi (ebi) Recombinant Protein | ebi recombinant protein

Recombinant Drosophila melanogaster F-box-like/WD repeat-containing protein ebi (ebi), partial

• Gene Names: ebi; CG4063; DmelCG4063; E-2f; E-2g; Ebi; FBXW4; l(2)k16213; Tb11; Tbl1
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: F-box-like/WD repeat-containing protein ebi (ebi); Recombinant Drosophila melanogaster F-box-like/WD repeat-containing protein ebi (ebi); partial; ebi recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 700

• Species: Drosophila melanogaster (Fruit fly)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 17137500
• NCBI GeneID: 33212
• NCBI Accession #: NP_477329.1
• NCBI GenBank Nucleotide #: NM_057981.4
• UniProt Accession #: Q95RJ9; Q9XZK1
• Molecular Weight: 72,387 Da
• NCBI Official Full Name: ebi
• NCBI Official Symbol: ebi
• NCBI Official Synonym Symbols: CG4063; DmelCG4063; E-2f; E-2g; Ebi; FBXW4; l(2)k16213; Tb11; Tbl1
• NCBI Protein Information: CG4063 gene product from transcript CG4063-RA
• UniProt Protein Name: F-box-like/WD repeat-containing protein ebi
• Protein Family: F-box-like/WD repeat-containing protein
• UniProt Gene Name: ebi

Uniprot Description

F-box-like component of E3 ubiquitin ligase complexes; involved in R7 photoreceptor cell differentiation, cone cell development and neuronal cell cycle control. E3 ubiquitin ligase complexes mediate ubiquitination and subsequent proteasomal degradation of target proteins. Required for specification of R7 photoreceptor cell fate in the eye by participating in the ubiquitination and subsequent proteasomal degradation of Tramtrack (ttk), a general inhibitor of photoreceptor differentiation. Required to block the S phase entry in the peripheral nervous system and central nervous system in a process that does not involve the degradation of ttk. Involved in cone cell development by preventing the transcriptional repression mediated by Su(H) on Dl, probably by participating in a E3 complex that contains sno and mediates the ubiquitination and subsequent proteasomal degradation of some component of the Su(H) repressor complex.