Western Blot (WB)
(Western blot analysis of MLL4 expression in HL60 (A), A549 (B), NIH3T3 (C), H9C2 (D) whole cell lysates.)
Rabbit MLL4 Polyclonal Antibody | anti-WBP7 antibody
Anti-MLL4 Antibody
Western Blot (WB)
(Western blot analysis of MLL4 expression in HL60 (A), A549 (B), NIH3T3 (C), H9C2 (D) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of MLL4 expression in HL60 (A), A549 (B), NIH3T3 (C), H9C2 (D) whole cell lysates.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known. [provided by RefSeq, Jul 2008]
Uniprot Description
MLL2: may be a transcriptional regulator. Contains 3 A.T hook DNA-binding domains. Two alternatively spliced isoforms have been described.
Protein type: EC 2.1.1.43; Methyltransferase, protein lysine; Transcription factor; DNA-binding; Methyltransferase
Chromosomal Location of Human Ortholog: 19q13.1
Cellular Component: nucleoplasm; histone methyltransferase complex; nucleus
Molecular Function: protein binding; DNA binding; zinc ion binding; histone lysine N-methyltransferase activity (H3-K4 specific); transcription factor activity
Biological Process: ovulation; establishment and/or maintenance of chromatin architecture; transcription, DNA-dependent; ovarian follicle development; chromatin-mediated maintenance of transcription; histone H3-K4 methylation; regulation of histone H3-K4 methylation; oocyte differentiation; gene silencing
Research Articles on WBP7
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Product Notes
The WBP7 kmt2b (Catalog #AAA821897) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-MLL4 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MLL4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB (1/500 - 1/1000). Researchers should empirically determine the suitability of the WBP7 kmt2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MLL4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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