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Neutrophil Activating Protein-2 Active Protein | rNAP 2 active protein

Recombinant Rat Neutrophil Activating Protein-2 (CXCL7)

Gene Names
Ppbp; Cxcl7; Nap-2
Purity
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Synonyms
Neutrophil Activating Protein-2; Recombinant Rat Neutrophil Activating Protein-2 (CXCL7); NAP 2 Rat; Neutrophil Activating Protein-2 Rat Recombinant (CXCL7); Platelet basic protein; PBP; Small inducible cytokine B7; CXCL7; Leukocyte-derived growth factor; LDGF; Macrophage-derived growth factor; MDGF; pro-platelet basic protein (chemokine (C-X-C motif) ligand 7); TC1; TC2; TGB; TGB1; B-TG1; CTAP3; NAP-2; SCYB7; THBGB; LA-PF4; THBGB1; Beta-TG; CTAPIII; CTAP-III; rNAP 2 active protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Form/Format
NAP-2 protein was lyophilized from a 0.2 um filtered concentrated solution in 1xPBS, pH 7.4.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sequence
IELRCRCTNT LSGIPLNSIS RVNVFRPGAH CDNVEVIATL KNGKEVCLDP TAPMIKKIVK KI
Sequence Length
111
Solubility
It is recommended to reconstitute the lyophilized NAP-2 in sterile 18M-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Biological Activity
Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CXCR2. The ED50 for this effect is less than 10ng/ml, corresponding to a specific activity of 100,000units/mg.
Preparation and Storage
Lyophilized NAP-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution CXCL7 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Related Product Information for rNAP 2 active protein
Description: NAP-2 Rat Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 62 amino acids and having a molecular mass of 6.8kDa.The NAP 2 is purified by proprietary chromatographic techniques.

Introduction: Chemokine (C-X-C motif) ligand (CXCL7) is a small cytokine belonging to the CXC chemokine family. It is a protein that is released in large amounts from platelets following their activation. It stimulates various processes including mitogenesis, synthesis of extracellular matrix, glucose metabolism and synthesis of plasminogen activator.
Product Categories/Family for rNAP 2 active protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
12,159 Da
NCBI Official Full Name
platelet basic protein
NCBI Official Synonym Full Names
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
NCBI Official Symbol
Ppbp
NCBI Official Synonym Symbols
Cxcl7; Nap-2
NCBI Protein Information
platelet basic protein; chemokine (C-X-C motif) ligand 7; neutrophil activating peptide-2
UniProt Protein Name
CXC chemokine RTCK1
UniProt Gene Name
Ppbp
UniProt Entry Name
Q99ME0_RAT

NCBI Description

has 72.6% amino acid sequence identity with the mouse homolog which displays increased expression in response to thrombopoietin stimulation [RGD, Feb 2006]

Research Articles on rNAP 2

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Product Notes

The rNAP 2 ppbp (Catalog #AAA145035) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: IELRCRCTNT LSGIPLNSIS RVNVFRPGAH CDNVEVIATL KNGKEVCLDP TAPMIKKIVK KI. It is sometimes possible for the material contained within the vial of "Neutrophil Activating Protein-2, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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