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RANTES (CCL 5) active protein

Mouse RANTES (CCL 5)

Gene Names
Ccl5; SISd; Scya5; RANTES; TCP228; MuRantes
Reactivity
Mouse
Purity
> 98% (SDS-PAGE; HPLC)
Synonyms
RANTES (CCL 5); Mouse RANTES (CCL 5); Recombinant Murine RANTES; RANTES (CCL 5) active protein
Ordering
For Research Use Only!
Host
E Coli
Reactivity
Mouse
Purity/Purification
> 98% (SDS-PAGE; HPLC)
Form/Format
Lyophilized
Sequence
SPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRN RQVC ANPEKKWVQE YINYLEMS
Sequence Length
91
Endotoxin Level
< 0.1 ng/ug of RANTES
Biological Activity
Determined by its ability to chemoattract total human lymphocyte population and total murine T cell population using a concentration range of 1.0-10.0 ng/ml.
Related Product Information for RANTES (CCL 5) active protein
RANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant murine RANTES is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
Product Categories/Family for RANTES (CCL 5) active protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
7.8 kDa
NCBI Official Full Name
C-C motif chemokine 5
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 5
NCBI Official Symbol
Ccl5
NCBI Official Synonym Symbols
SISd; Scya5; RANTES; TCP228; MuRantes
NCBI Protein Information
C-C motif chemokine 5; SIS-delta; small inducible cytokine A5; small-inducible cytokine A5; T-cell-specific protein RANTES
UniProt Protein Name
C-C motif chemokine 5
UniProt Gene Name
Ccl5
UniProt Synonym Gene Names
Scya5
UniProt Entry Name
CCL5_MOUSE

Uniprot Description

Function: Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils.

Subcellular location: Secreted.

Tissue specificity: T-cell and macrophage specific.

Sequence similarities: Belongs to the intercrine beta (chemokine CC) family.

Research Articles on RANTES (CCL 5)

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Product Notes

The RANTES (CCL 5) ccl5 (Catalog #AAA691610) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Mouse RANTES (CCL 5) reacts with Mouse and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: SPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRN RQVC ANPEKKWVQE YINYLEMS. It is sometimes possible for the material contained within the vial of "RANTES (CCL 5), Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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