IL-5 active protein
Mouse IL-5
Gene Names
Il5; Il-5
Reactivity
Mouse
Purity
> 98% by SDS-PAGE & HPLC analyses
Synonyms
IL-5; Mouse IL-5; Il5; Il-5; B-cell growth factor II Short name=BCGF-II Cytotoxic T-lymphocyte inducer Eosinophil differentiation factor T-cell replacing factor; IL-5 active protein
Host
E Coli
Reactivity
Mouse
Purity/Purification
> 98% by SDS-PAGE & HPLC analyses
Form/Format
Lyophilized
Sequence
MEIPMSTVVK ETLTQLSAHR ALLTSNETMR LPVPTHKNHQ LCIGEI FQGL DILKNQTVRG GTVEMLFQNL SLIKKYIDRQ KEKCGEERRR T RQFLDYLQE FLGVMSTEWA MEG
Sequence Length
133
Biological Activity
The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells and is < 2.0 ng/ml, corresponding to a specific activity of > 5 x 10^5 units/mg.
Related Product Information for IL-5 active protein
IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 is cross-species reactive. Recombinant murine IL-5 is a 26.2 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains.
Product Categories/Family for IL-5 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
15,410 Da
NCBI Official Full Name
interleukin-5
NCBI Official Synonym Full Names
interleukin 5
NCBI Official Symbol
Il5
NCBI Official Synonym Symbols
Il-5
NCBI Protein Information
interleukin-5; TRF; BCGF-II; B-cell growth factor II; T-cell replacing factor; cytotoxic T-lymphocyte inducer; eosinophil differentiation factor
UniProt Protein Name
Interleukin-5
UniProt Gene Name
Il5
UniProt Synonym Gene Names
Il-5; IL-5; BCGF-II; TRF
UniProt Entry Name
IL5_MOUSE
Uniprot Description
Function: Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.
Subunit structure: Homodimer; disulfide-linked.
Subcellular location: Secreted.
Sequence similarities: Belongs to the IL-5 family.
Research Articles on IL-5
Similar Products
Product Notes
The IL-5 il5 (Catalog #AAA691820) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Mouse IL-5 reacts with Mouse and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: MEIPMSTVVK ETLTQLSAHR ALLTSNETMR LPVPTHKNHQ LCIGEI FQGL DILKNQTVRG GTVEMLFQNL SLIKKYIDRQ KEKCGEERRR T RQFLDYLQE FLGVMSTEWA MEG. It is sometimes possible for the material contained within the vial of "IL-5, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
