IL-11 active protein
Mouse IL-11
Gene Names
Il11; IL-11
Reactivity
Mouse
Purity
> 98% by SDS-PAGE
Synonyms
IL-11; Mouse IL-11; Recombinant Murine IL-11; IL-11 active protein
Host
E Coli
Reactivity
Mouse
Purity/Purification
> 98% by SDS-PAGE
Form/Format
Lyophilized
Sequence
MPGPPAGSPR VSSDPRADLD SAVLLTRSLL ADTRQLAAQM RDKFPA DGDH SLDSLPTLAM SAGTLGSLQL PGVLTRLRVD LMSYLRHVQW L RRAGGPSLK TLEPELGALQ ARLERLLRRL QLLMSRLALP QAAPDQP VIP LGPPASAWGS IRAAHAILGG LHLTLDWAVR GLLLLKTRL
Sequence Length
199
Endotoxin Level
< 0.1 ng per ug of IL-11
Biological Activity
The ED50 was determined by the dose-dependent stimulation of the proliferation of murine T11 cells is <= 2.0 ng/ml, corresponding to a specific activity of >= 5 x 105 units/mg.
Related Product Information for IL-11 active protein
IL-11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL-11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury. Recombinant Murine IL-11 is a 19.1 kDa protein consisting of 179 amino acid residues.
Product Categories/Family for IL-11 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
19.1 kDa
NCBI Official Full Name
interleukin-11
NCBI Official Synonym Full Names
interleukin 11
NCBI Official Symbol
Il11
NCBI Official Synonym Symbols
IL-11
NCBI Protein Information
interleukin-11
UniProt Protein Name
Interleukin-11
UniProt Gene Name
Il11
UniProt Synonym Gene Names
IL-11
UniProt Entry Name
IL11_MOUSE
Uniprot Description
Function: Directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production.
Subcellular location: Secreted.
Sequence similarities: Belongs to the IL-6 superfamily.
Research Articles on IL-11
Similar Products
Product Notes
The IL-11 il11 (Catalog #AAA691494) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Mouse IL-11 reacts with Mouse and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: MPGPPAGSPR VSSDPRADLD SAVLLTRSLL ADTRQLAAQM RDKFPA DGDH SLDSLPTLAM SAGTLGSLQL PGVLTRLRVD LMSYLRHVQW L RRAGGPSLK TLEPELGALQ ARLERLLRRL QLLMSRLALP QAAPDQP VIP LGPPASAWGS IRAAHAILGG LHLTLDWAVR GLLLLKTRL. It is sometimes possible for the material contained within the vial of "IL-11, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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