Beta Defensin -1 Active Protein | mBD 1 active protein
Recombinant Mouse Beta Defensin -1
Gene Names
Defb1; BD-1; AW260221
Purity
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Synonyms
Beta Defensin -1; Recombinant Mouse Beta Defensin -1; BD 1 Mouse; Beta Defensin-1 Mouse Recombinant; Beta-defensin 1; BD-1; Defensin beta 1; hBD-1; HBD1; HBP1; DEFB1; HBD-1; HBP-1; DEFB101; DEFB-1; MGC51822; mBD 1 active protein
Host
E Coli
Purity/Purification
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Form/Format
Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH7.4.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sequence
DQYKCLQHGG FCLRSSCPSN TKLQGTCKPD KPNCCKS
Sequence Length
69
Solubility
It is recommended to reconstitute the lyophilized Mouse BD-1 in sterile 18M-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Biological Activity
Measured by its ability to chemoattract CD34+ dendritic cells using a concentration range of 0.1-1.0 ug/ml, corresponding to a specific activity of 1,000-10,000units/mg.
Related Product Information for mBD 1 active protein
Description: BD 1 Mouse Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 37 amino acids and having a molecular mass of 4.1 KDa.The BD 1 Mouse is purified by proprietary chromatographic techniques.
Introduction: The Defensin family are highly similar in their protein sequence and are microbicidal & cytotoxic peptides made by neutrophils. Beta Defensin-1 is an antimicrobial peptide having the resistance of epithelial surfaces to microbial colonization. Beta Defensin-1 has close proximity to Defensin Alpha-1 and has been implicated in the pathogenesis of cystic fibrosis.Skin of patients having atopic dermatitis patients and mycosis fungoides (non-lesional and lesional) show lower human Beta Defensin-1 mRNA expression and higher human Beta Defensin-2 and human Beta Defensin-3 mRNA expression. Beta Defensin is highly expressed by epithelial cells. Beta-defensin 1 may play a role in the pathogenesis of severe sepsis.
Introduction: The Defensin family are highly similar in their protein sequence and are microbicidal & cytotoxic peptides made by neutrophils. Beta Defensin-1 is an antimicrobial peptide having the resistance of epithelial surfaces to microbial colonization. Beta Defensin-1 has close proximity to Defensin Alpha-1 and has been implicated in the pathogenesis of cystic fibrosis.Skin of patients having atopic dermatitis patients and mycosis fungoides (non-lesional and lesional) show lower human Beta Defensin-1 mRNA expression and higher human Beta Defensin-2 and human Beta Defensin-3 mRNA expression. Beta Defensin is highly expressed by epithelial cells. Beta-defensin 1 may play a role in the pathogenesis of severe sepsis.
Product Categories/Family for mBD 1 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
7,749 Da
NCBI Official Full Name
beta-defensin 1
NCBI Official Synonym Full Names
defensin beta 1
NCBI Official Symbol
Defb1
NCBI Official Synonym Symbols
BD-1; AW260221
NCBI Protein Information
beta-defensin 1
UniProt Protein Name
Beta-defensin 1
UniProt Gene Name
Defb1
UniProt Synonym Gene Names
BD-1; mBD-1
UniProt Entry Name
DEFB1_MOUSE
Uniprot Description
defensin, beta 1: Has bactericidal activity. Belongs to the beta-defensin family.
Protein type: Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis
Cellular Component: extracellular region
Biological Process: response to bacterium; defense response to bacterium; innate immune response; defense response
Research Articles on mBD 1
Similar Products
Product Notes
The mBD 1 defb1 (Catalog #AAA144745) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: DQYKCLQHGG FCLRSSCPSN TKLQGTCKPD KPNCCKS. It is sometimes possible for the material contained within the vial of "Beta Defensin -1, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
