Rabbit anti-Human CCL17 Polyclonal Antibody | anti-CCL17 antibody

CCL17 Rabbit Polyclonal

Cat. Num. AAA767611

• Gene Names: CCL17; TARC; ABCD-2; SCYA17; A-152E5.3
• Reactivity: Human
• Applications: ELISA, Immunohistochemistry, Western Blot
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: CCL17; Polyclonal Antibody; CCL17 Rabbit Polyclonal; anti-CCL17 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 94

• Applicable Applications for anti-CCL17 antibody: ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
• Immunogen: Chemokine (C-C motif) ligand 17
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded rat heart using MBS767611 (CCL17 Antibody) at dilution of 1:50)

Western Blot (WB)

(Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with MBS767611 (CCL17 Antibody) at dilution of 1:1000)

NCBI and Uniprot Product Information

• NCBI GI #: 4506829
• NCBI GeneID: 6361
• NCBI Accession #: NP_002978.1
• NCBI GenBank Nucleotide #: NM_002987.2
• Molecular Weight: 10,507 Da
• NCBI Official Full Name: C-C motif chemokine 17
• NCBI Official Synonym Full Names: C-C motif chemokine ligand 17
• NCBI Official Symbol: CCL17
• NCBI Official Synonym Symbols: TARC; ABCD-2; SCYA17; A-152E5.3
• NCBI Protein Information: C-C motif chemokine 17
• UniProt Protein Name: C-C motif chemokine 17
• Protein Family: C-C motif chemokine
• UniProt Gene Name: CCL17
• UniProt Synonym Gene Names: SCYA17; TARC
• UniProt Entry Name: CCL17_HUMAN

NCBI Description

This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq, Sep 2014]

Uniprot Description

CCL17: Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 16q13

Cellular Component: extracellular region; extracellular space

Molecular Function: CCR chemokine receptor binding; chemokine activity; receptor binding

Biological Process: cell-cell signaling; chemotaxis; G-protein coupled receptor protein signaling pathway; inflammatory response; lymphocyte chemotaxis; monocyte chemotaxis; multicellular organismal development; negative regulation of myoblast differentiation; neutrophil chemotaxis; positive regulation of GTPase activity