Testing Data
Exodus-2 Active Protein | CCL21 active protein
Murine Exodus-2 (CCL21)
Gene Names
Gm10591; ENSMUSG00000073869
Reactivity
Species Reactivity: MouseCross Reactivity: Human
Purity
Above 98% as determined by SDS-PAGE Analysis.
Synonyms
Exodus-2; Murine Exodus-2 (CCL21); Recombinant Murine Exodus-2 (CCL21); CCL21 active protein
Host
E Coli
Reactivity
Species Reactivity: Mouse
Cross Reactivity: Human
Cross Reactivity: Human
Purity/Purification
Above 98% as determined by SDS-PAGE Analysis.
Sequence
SDGGGQDCC LKYSQKKIP YSIVRGYRK QEPSLGCPI PAILFLPRK HSKPELCAN PEEGWVQNL MRRLDQPPA PGKQSPGCR KNRGTSKSG KKGKGSKGC KRTEQTQPS RG
Biological Activity
Determined by its ability to chemoattract total murine T cell population using a concentration range of 10.0-100.0 ng/ml.
Cell Type
B Cells, T Cells, Endothelial Cells
Preparation and Storage
At -20 degree C
Testing Data
Testing Data
Related Product Information for CCL21 active protein
Exodus-2 is a CC chemokine that can signal through the CCR7 receptor. It is expressed in lymph nodes of certain endothelial cells, and in the spleen and appendix. Exodus-2 chemoattracts T and B lymphocytes and inhibits hematopoiesis. Exodus-2 contains six cysteine residues, including the four conserved cysteines present in CC chemokines. Recombinant murine Exodus-2 is a 12.0 kDa protein containing 110 amino acid residues.
Product Categories/Family for CCL21 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
14,584 Da
NCBI Official Full Name
C-C motif chemokine 21b
NCBI Official Synonym Full Names
predicted gene 10591
NCBI Official Symbol
Gm10591
NCBI Official Synonym Symbols
ENSMUSG00000073869
NCBI Protein Information
predicted gene 10591
UniProt Protein Name
C-C motif chemokine 21b
Protein Family
UniProt Gene Name
Ccl21b
UniProt Synonym Gene Names
Scya21; Scya21b; TCA4
UniProt Entry Name
CC21B_MOUSE
Uniprot Description
CCL21b: Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Potent mesangial cell chemoattractant. Shows preferential activity towards naive T- cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Belongs to the intercrine beta (chemokine CC) family.
Protein type: Chemokine; Motility/polarity/chemotaxis
Cellular Component: external side of plasma membrane
Molecular Function: chemokine receptor binding; chemokine activity
Biological Process: negative regulation of myeloid cell differentiation; leukocyte chemotaxis
Similar Products
Product Notes
The CCL21 ccl21b (Catalog #AAA696182) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Murine Exodus-2 (CCL21) reacts with Species Reactivity: Mouse Cross Reactivity: Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: SDGGGQDCC LKYSQKKIP YSIVRGYRK QEPSLGCPI PAILFLPRK HSKPELCAN PEEGWVQNL MRRLDQPPA PGKQSPGCR KNRGTSKSG KKGKGSKGC KRTEQTQPS RG. It is sometimes possible for the material contained within the vial of "Exodus-2, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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