mcp3 active protein
MCP3, Recombinant, Human (Macrophage/Monocyte Chemotactic Protein 3)
Purity
Highly PurifiedGreater than 99% by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng perug of MCP-3.
Synonyms
MCP3; Recombinant; Human (Macrophage/Monocyte Chemotactic Protein 3); mcp3 active protein
Host
E Coli
Purity/Purification
Highly Purified
Greater than 99% by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng perug of MCP-3.
Greater than 99% by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng perug of MCP-3.
Form/Format
Lyophilized protein with no additives.
Biological Activity
Human MCP-3 produced a 10-fold increase in chemotaxis at 100 ng/ml compared to the medium control in an assay using differentiated HL-60 cells plated on a primary endothelial cell layer. The assays were done using microporous cell culture inserts of 3µ pore size that were not protein coated.
Reconstitution
The lyophilized MCP-3 is soluble in water and most aqueous buffers. The lyophilized MCP-3 can be reconstituted in water to a concentration of 0.1 mg/ml. This solution can be diluted into other buffered solutions or stored frozen for future use.
Preparation and Storage
-20 degree C
Stability: The lyophilized protein, though stable at room temperature, is best stored desiccated below 0 degree C.
Stability: The lyophilized protein, though stable at room temperature, is best stored desiccated below 0 degree C.
Related Product Information for mcp3 active protein
Human macrophage/monocyte chemotactic protein-3 (MCP-3) is a 8.5kD protein containing 76 amino acids residues. It plays an important role in the inflammatory response of blood monocytes, tissue macrophages, and eosinophils.
The gene encoding this protein encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q.
The gene encoding this protein encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q.
Product Categories/Family for mcp3 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
8.5kD
NCBI Official Full Name
methyl-accepting chemotaxis protein
NCBI Official Symbol
mcp3
NCBI Protein Information
methyl-accepting chemotaxis protein
Protein Family
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Product Notes
The mcp3 (Catalog #AAA650858) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "MCP3, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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