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SDS-PAGE

Interleukin-13 protein (Il13) Active Protein | Il13 active protein

Recombinant Mouse Interleukin-13 protein (Il13) (Active)

Gene Names
Il13; Il-13
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Interleukin-13 protein (Il13); Recombinant Mouse Interleukin-13 protein (Il13) (Active); IL-13; Il13 active protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized
Sequence Positions
22-131aa
Sequence
M+PVPRSVSLP LTLKELIEEL SNITQDQTPL CNGSMVWSVD LAAGGFCVAL DSLTNISNCN AIYRTQRILH GLCNRKAPTT VSSLPDTKIE VAHFITKLLS YTKQLFRHGP F
Sequence Length
131
Species
Mus musculus (Mouse)
Biological Activity
Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 4 ng/ml, corresponding to a specific activity of > 2.5 × 105 IU/mg.
Endotoxin
Less than 1.0 EU/ug as determined by LAL method.
Protein Note
Protein will be provided with aseptic processing and endotoxin removal.
Preparation and Storage
Generally, the shelf life of liquid form is 6 months at -20/-80 degree C. The shelf life of lyophilized form is 12 months at -20/-80 degree C.

SDS-PAGE

SDS-PAGE
Related Product Information for Il13 active protein
Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses (By similarity). {ECO:0000250}.
Product Categories/Family for Il13 active protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
12.3 kDa
NCBI Official Full Name
interleukin-13
NCBI Official Synonym Full Names
interleukin 13
NCBI Official Symbol
Il13
NCBI Official Synonym Symbols
Il-13
NCBI Protein Information
interleukin-13
UniProt Protein Name
Interleukin-13
Protein Family
UniProt Gene Name
Il13
UniProt Synonym Gene Names
Il-13; IL-13

Uniprot Description

IL13: Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Defects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH). Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure. Belongs to the IL-4/IL-13 family.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 11 B1.3|11 31.98 cM

Cellular Component: cytoplasm; external side of plasma membrane; extracellular region; extracellular space

Molecular Function: interleukin-13 receptor binding

Biological Process: inflammatory response; microglial cell activation; negative regulation of NAD(P)H oxidase activity; positive regulation of B cell proliferation; positive regulation of connective tissue growth factor production; positive regulation of immunoglobulin production; positive regulation of ion transport; positive regulation of macrophage activation; positive regulation of mast cell degranulation; positive regulation of protein secretion; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of smooth muscle cell proliferation; positive regulation of tyrosine phosphorylation of STAT protein; regulation of proton transport; response to nicotine

Research Articles on Il13

Similar Products

Product Notes

The Il13 il13 (Catalog #AAA969455) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 22-131aa. The amino acid sequence is listed below: M+PVPRSVSL P LTLKELIEEL SNITQDQTPL CNGSMVWSVD LAAGGFCVAL DSLTNISNCN AIYRTQRILH GLCNRKAPTT VSSLPDTKIE VAHFITKLLS YTKQLFRHGP F. It is sometimes possible for the material contained within the vial of "Interleukin-13 protein (Il13), Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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