Interferon alpha-2 (IFNA2) Active Protein | IFNA2 active protein
Recombinant Human Interferon alpha-2 (IFNA2)
Gene Names
IFNA2; IFNA; INFA2; IFNA2B; IFN-alphaA
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Interferon alpha-2 (IFNA2); Recombinant Human Interferon alpha-2 (IFNA2); Interferon Alpha-2; IFN-Alpha-2; Interferon Alpha-A; LeIF A; IFNA2; IFNA2 active protein
Host
E Coli
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized from a 0.2 mum Filtered 20 mM PB, 150 mM NaCl, pH 7.2
Sequence Positions
24-188aa; Full Length of Mature Protein
Sequence
CDLPQTHSLGSRRTLMLLAQMRKISLFSCLKDRHDFGFPQEEFGNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLEACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTNLQESLRSKE
Sequence Length
188
Species
Human
Tag
Tag-Free
Endotoxin
Less than 1.0 EU/ug as determined by LAL method.
Biological Activity
The ED50 as determined by a viral resistance assay using VSV-WISH cells is less than 10 pg/mL.
Subcellular Location
Secreted
Protein Families
Alpha/beta Interferon Family
Classification
Cytokine
Subdivision
Interferon
Pathway
Jak-STAT Signaling Pathway
Preparation and Storage
Store at -20 degree C. For extended storage, conserve at -20 degree C or -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Related Product Information for IFNA2 active protein
Relevance: At least 23 different variants of IFN-alpha are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-alpha subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-alpha subtypes differ in their sequences by only one or two positions. Naturally occurring variants also include proteins that are truncated by 10 amino acids at the carboxyl-terminal end.
Function: Produced by macrophages, IFN-alpha have antiviral activities.
Function: Produced by macrophages, IFN-alpha have antiviral activities.
Product Categories/Family for IFNA2 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
19.4 kDa
NCBI Official Full Name
interferon alpha-2
NCBI Official Synonym Full Names
interferon alpha 2
NCBI Official Symbol
IFNA2
NCBI Official Synonym Symbols
IFNA; INFA2; IFNA2B; IFN-alphaA
NCBI Protein Information
interferon alpha-2
UniProt Protein Name
Interferon alpha-2
UniProt Gene Name
IFNA2
UniProt Synonym Gene Names
IFNA2A; IFNA2B; IFNA2C; IFN-alpha-2; LeIF A
UniProt Entry Name
IFNA2_HUMAN
NCBI Description
This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Use of the recombinant form of this protein has been shown to be effective in reducing the symptoms and duration of the common cold. [provided by RefSeq, Jun 2011]
Research Articles on IFNA2
Similar Products
Product Notes
The IFNA2 ifna2 (Catalog #AAA7115016) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 24-188aa; Full Length of Mature Protein. The amino acid sequence is listed below: CDLPQTHSLG SRRTLMLLAQ MRKISLFSCL KDRHDFGFPQ EEFGNQFQKA ETIPVLHEMI QQIFNLFSTK DSSAAWDETL LDKFYTELYQ QLNDLEACVI QGVGVTETPL MKEDSILAVR KYFQRITLYL KEKKYSPCAW EVVRAEIMRS FSLSTNLQES LRSKE. It is sometimes possible for the material contained within the vial of "Interferon alpha-2 (IFNA2), Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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