GM-CSF active protein
Mouse GM-CSF
Gene Names
Csf2; Csfgm; GMCSF; Gm-CSf; MGI-IGM
Reactivity
Mouse
Purity
> 98% by SDS-PAGE & HPLC analyses
Synonyms
GM-CSF; Mouse GM-CSF; Granulocyte Macrophage Colony-Stimulating Factor; CSF-2; MGI-1GM; pluripoietin-alpha; GM-CSF active protein
Host
E Coli
Reactivity
Mouse
Purity/Purification
> 98% by SDS-PAGE & HPLC analyses
Form/Format
Lyophilized
Sequence
MAPTRSPITV TRPWKHVEAI KEALNLLDDM PVTLNEEVEV VSNEFS FKKL TCVQTRLKIF EQGLRGNFTK LKGALNMTAS YYQTYCPPTP E TDCETQVTT YADFIDSLKT FLTDIPFECK KPVQK
Sequence Length
141
Biological Activity
The ED50 as determined by the dose-dependent stimulation of the proliferation of murine FDC-P1 cells is <= 0.05 ng/ml, corresponding to a specific activity of >= 2 x 107 units/mg.
Related Product Information for GM-CSF active protein
GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant murine GM-CSF is a 14.2 kDa globular protein consisting of 125 amino acid residues.
Product Categories/Family for GM-CSF active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
16,091 Da
NCBI Official Full Name
granulocyte-macrophage colony-stimulating factor
NCBI Official Synonym Full Names
colony stimulating factor 2 (granulocyte-macrophage)
NCBI Official Symbol
Csf2
NCBI Official Synonym Symbols
Csfgm; GMCSF; Gm-CSf; MGI-IGM
NCBI Protein Information
granulocyte-macrophage colony-stimulating factor; CSF; put. GM-CSF; granulocyte-macrophage colony stimulating factor 2
UniProt Protein Name
Granulocyte-macrophage colony-stimulating factor
UniProt Gene Name
Csf2
UniProt Synonym Gene Names
Csfgm; GM-CSF; CSF
UniProt Entry Name
CSF2_MOUSE
Uniprot Description
Function: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
Subunit structure: Monomer. The signaling GM-CSF receptor complex is a dodecamer of two head-to-head hexamers of two alpha, two beta, and two ligand subunits
By similarity.
Subcellular location: Secreted.
Sequence similarities: Belongs to the GM-CSF family.
Sequence caution: The sequence CAA26192.1 differs from that shown. Reason: Erroneous initiation.
Research Articles on GM-CSF
Similar Products
Product Notes
The GM-CSF csf2 (Catalog #AAA691599) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Mouse GM-CSF reacts with Mouse and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: MAPTRSPITV TRPWKHVEAI KEALNLLDDM PVTLNEEVEV VSNEFS FKKL TCVQTRLKIF EQGLRGNFTK LKGALNMTAS YYQTYCPPTP E TDCETQVTT YADFIDSLKT FLTDIPFECK KPVQK. It is sometimes possible for the material contained within the vial of "GM-CSF, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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