4-1 BB Receptor Active Protein
4-1 BB Receptor, Recombinant, Human (CD137, 4-1BB Ligand Receptor, TNFRSF9, CDw137, ILA, MGC2172, T-cell antigen 4-1BB homolog)
Purity
Highly Purified98% by SDS-PAGE and HPLC analyses
Synonyms
4-1 BB Receptor; Recombinant; Human (CD137; 4-1BB Ligand Receptor; TNFRSF9; CDw137; ILA; MGC2172; T-cell antigen 4-1BB homolog); 4-1 BB Receptor active protein
Host
E Coli
Purity/Purification
Highly Purified
98% by SDS-PAGE and HPLC analyses
98% by SDS-PAGE and HPLC analyses
Form/Format
The sterile ltered solution was lyophilized from 0.3X PBS.
Sequence
MERTRSLQDP CSNCPAGTFC DNNRNQICSP CPPNSFSSAG GQRTCDICRQ CKGVFRTRKE CSSTSNAECD CTPGFHCLGA GCSMCEQDCK QGQELTKKGC KNCCFGTFND QKRGICRPWT NCSLDGKSVL VNGTKERDVV CGPSPADLSP GASSVTPPAP AREPGHS
Biological Activity
Determined by its inhibitory effect of the 4-1BBL mediated stimulation of IL-8 production by human PBMC (peripheral blood mononuclear cells). About 90% of inibition was seen using a concentration of 1ug for both 4-1BBL and 4-1BBR.
Country of Origin
USA
Endotoxin Level
0.1ng/ug (1EU/ug).
Reconstitution
We recommend a quick spin followed by reconsitution in water to a concentration of 0.1-1.0mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4 degree C for 1 week or -20 degree C for future use.
Preparation and Storage
The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20 degree C. Reconstituted 4-1BBL should be stored in working aliquots at -20 degree C.
Related Product Information for 4-1 BB Receptor active protein
Human 4-1BB Receptor (4-1BBR) is an inhibitor of 4-1BBL and can block 4-1BBL bioactivity. Human 4-1BBR is a 17.7kDa protein consisting of 167 amino acid residues.
Product Categories/Family for 4-1 BB Receptor active protein
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Product Notes
The 4-1 BB Receptor (Catalog #AAA650296) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MERTRSLQDP CSNCPAGTFC DNNRNQICSP CPPNSFSSAG GQRTCDICRQ CKGVFRTRKE CSSTSNAECD CTPGFHCLGA GCSMCEQDCK QGQELTKKGC KNCCFGTFND QKRGICRPWT NCSLDGKSVL VNGTKERDVV CGPSPADLSP GASSVTPPAP AREPGHS. It is sometimes possible for the material contained within the vial of "4-1 BB Receptor, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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