Testing Data
4-1 BBL Active Protein | 4-1BB active protein
Human 4-1 BBL
Reactivity
Species Reactivity: Human
Purity
Above 98% as determined by SDS-PAGE Analysis.
Synonyms
4-1 BBL; Human 4-1 BBL; Recombinant Human 4-1BB Ligand; 4-1BB active protein
Host
E Coli
Reactivity
Species Reactivity: Human
Purity/Purification
Above 98% as determined by SDS-PAGE Analysis.
Sequence
MREGPELSP DDPAGLLDL RQGMFAQLV AQNVLLIDG PLSWYSDPG LAGVSLTGG LSYKEDTKE LVVAKAGVY YVFFQLELR RVVAGEGSG SVSLALHLQ PLRSAAGAA ALALTVDLP PASSEARNS AFGFQGRLL HLSAGQRLG VHLHTEARA RHAWQLTQG ATVLGLFRV TPEIPAGLP SPRSE
Biological Activity
Determined by the dose-dependent stimulation of IL-8 production by human PBMC. The ED50 for this effect is 5-10 ng/ml. Please Note: Results may vary with PBMC donors.
Cell Type
T Cells
Preparation and Storage
At -20 degree C
Testing Data
Testing Data
Related Product Information for 4-1BB active protein
4-1BBL, a member of the TNF superfamily, is expressed in B cells, dendritic cells, activated T cells and macrophages. 4-1BBL binds to its receptor 4-1BB, and provides a co-stimulatory signal for T cell activation and expansion. The human 4-1BBL gene codes for a 254 amino acid type II transmembrane containing a 28 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 205 amino acid extracellular domain. The soluble form of 4-1BBL contains the TNF-like portion of the extracellular domain of 4-1BBL. Recombinant human 4-1BBL is a soluble 19.5 kDa protein consisting of 185 amino acid residues.
Product Categories/Family for 4-1BB active protein
NCBI and Uniprot Product Information
UniProt Accession #
Similar Products
Product Notes
The 4-1BB (Catalog #AAA695792) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Human 4-1 BBL reacts with Species Reactivity: Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: MREGPELSP DDPAGLLDL RQGMFAQLV AQNVLLIDG PLSWYSDPG LAGVSLTGG LSYKEDTKE LVVAKAGVY YVFFQLELR RVVAGEGSG SVSLALHLQ PLRSAAGAA ALALTVDLP PASSEARNS AFGFQGRLL HLSAGQRLG VHLHTEARA RHAWQLTQG ATVLGLFRV TPEIPAGLP SPRSE. It is sometimes possible for the material contained within the vial of "4-1 BBL, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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