Human dynein, light chain, Tctex-type 3 ELISA Kit | DYNLT3 elisa kit
Human Dynein light chain Tctex-type 3, DYNLT3 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of a subclass of dynein light chains. The encoded protein homodimerizes and forms the light chain component of the cytoplasmic dynein motor protein complex. This protein may be important for binding dynein to specific cargos including the spindle checkpoint protein BUB3. This protein may also function independently of dynein as a transcriptional modulator. Pseudogenes of this gene are found on chromosomes 2 and 20.[provided by RefSeq, Mar 2010]
Uniprot Description
DYNLT3: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis. Belongs to the dynein light chain Tctex-type family.
Protein type: Microtubule-binding; Motor
Chromosomal Location of Human Ortholog: Xp21
Cellular Component: kinetochore; microtubule; cytoplasmic dynein complex; nucleus
Molecular Function: identical protein binding; motor activity
Biological Process: mitosis; metabolic process; transport; cell division; regulation of mitotic cell cycle
Research Articles on DYNLT3
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Product Notes
The Human DYNLT3 dynlt3 (Catalog #AAA9320761) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9320761 ELISA Kit recognizes Human DYNLT3. It is sometimes possible for the material contained within the vial of "dynein, light chain, Tctex-type 3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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