Rat Dual specificity protein phosphatase 4 ELISA Kit | Dusp4 elisa kit
Rat Dual specificity protein phosphatase 4 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
exhibits vanadate-sensitive phosphatase activity for MAP kinase; inhibits transcription of MAP kinase-dependent genes [RGD, Feb 2006]
Uniprot Description
MKP-2: a non-receptor, dual-specificity phosphoprotein phosphatase (DUSP). Different members of the DUSP family show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP4 inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Induced by hepatocyte growth factor (HGF) and vascular endothelial cell growth factor (VEGF) in human endothelial cells. Two alternatively spliced isoforms have been described. In addition, multiple polyadenylation sites have been reported. Contains 1 rhodanese domain.
Protein type: Protein phosphatase, dual-specificity; EC 3.1.3.48; EC 3.1.3.16
Cellular Component: nucleoplasm; nucleus
Molecular Function: MAP kinase tyrosine/serine/threonine phosphatase activity; protein tyrosine phosphatase activity; protein tyrosine/threonine phosphatase activity
Biological Process: endoderm formation; inactivation of MAPK activity; protein amino acid dephosphorylation
Research Articles on Dusp4
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Product Notes
The Rat Dusp4 dusp4 (Catalog #AAA2885922) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2885922 ELISA Kit recognizes Rat Dusp4. It is sometimes possible for the material contained within the vial of "Dual specificity protein phosphatase 4, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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