SDS-Page
DuSP19 recombinant protein
DuSP19, 65-217aa, Human, His tag, E Coli
Gene Names
DUSP19; SKRP1; DUSP17; LMWDSP3; TS-DSP1
Applications
SDS-Page
Purity
> 90% by SDS-PAGE
Synonyms
DuSP19; 65-217aa; Human; His tag; E Coli; Dual specificity phosphatase 19; DuSP17; SKRP1; TS-DSP1; DuSP19 recombinant protein
Host
E Coli
Purity/Purification
> 90% by SDS-PAGE
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl
Concentration
0.5 mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MGSSHHHHHH SSGLVPRGSH MGSQVGVIKP WLLLGSQDAA HDLDTLKKNK VTHILNVAYG VENAFLSDFT YKSISILDLP ETNILSYFPE CFEFIEEAKR KDGVVLVHCN AGVSRAAAIV IGFLMNSEQT SFTSAFSLVK NARPSICPNS GFMEQLRTYQ EGKESNKCDR IQENSS
Sequence Length
217
Applicable Applications for DuSP19 recombinant protein
SDS-PAGE
Antigen Species
Human
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
SDS-Page
SDS-Page
Related Product Information for DuSP19 recombinant protein
Dual specificity phosphatase 19, also known as DuSP19, is a member of the dual specificity protein phosphatase subfamily. DuSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DuSP19 is a protein phosphatase which functions as a stress-activated protein kinase pathway-regulating phosphatase. DuSP19 contains a variation of the consensus DuSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP class of DuSPs. Recombinant human DuSP19 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
Product Categories/Family for DuSP19 recombinant protein
References
Cheng H., et al. (2003) Int J BoiChem Cell Biol. 35 (2):226-34.; Zama Takeru., et al. (2002) J Boil Chem. 277 (26):23909-18.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
19.4 kDa (176aa), confirmed by MALDI-TOF
NCBI Official Full Name
dual specificity protein phosphatase 19 isoform 1
NCBI Official Synonym Full Names
dual specificity phosphatase 19
NCBI Official Symbol
DUSP19
NCBI Official Synonym Symbols
SKRP1; DUSP17; LMWDSP3; TS-DSP1
NCBI Protein Information
dual specificity protein phosphatase 19
UniProt Protein Name
Dual specificity protein phosphatase 19
Protein Family
UniProt Gene Name
DUSP19
UniProt Synonym Gene Names
DUSP17; LMWDSP3; SKRP1; LMW-DSP3; SAPK pathway-regulating phosphatase 1
NCBI Description
Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP19 contains a variation of the consensus DUSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009]
Uniprot Description
Has a dual specificity toward Ser/Thr and Tyr-containing proteins.
Research Articles on DuSP19
Similar Products
Product Notes
The DuSP19 dusp19 (Catalog #AAA204156) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is His-tag. AAA Biotech's DuSP19 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the DuSP19 dusp19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MGSQVGVIKP WLLLGSQDAA HDLDTLKKNK VTHILNVAYG VENAFLSDFT YKSISILDLP ETNILSYFPE CFEFIEEAKR KDGVVLVHCN AGVSRAAAIV IGFLMNSEQT SFTSAFSLVK NARPSICPNS GFMEQLRTYQ EGKESNKCDR IQENSS. It is sometimes possible for the material contained within the vial of "DuSP19, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
