VPS25 blocking peptide
VPS25 Immunizing Peptide
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that is a subunit of the endosomal sorting complex required for transport II (ESCRT-II). This protein complex functions in sorting of ubiquitinated membrane proteins during endocytosis. A pseudogene of this gene is present on chromosome 1. [provided by RefSeq, Jul 2013]
Uniprot Description
VPS25: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. The ESCRT-II complex may be involved in facilitating the budding of certain RNA viruses. Belongs to the VPS25 family.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 17q21.31
Cellular Component: cytoplasm; cytosol; endosome membrane; nucleolus; nucleoplasm; nucleus
Molecular Function: protein binding; protein homodimerization activity; protein N-terminus binding; structural molecule activity
Biological Process: autophagy; endosome transport; protein targeting to vacuole during ubiquitin-dependent protein catabolic process via the MVB pathway; regulation of transcription, DNA-dependent; transcription, DNA-dependent
Research Articles on VPS25
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Product Notes
The VPS25 vps25 (Catalog #AAA426294) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The VPS25 Immunizing Peptide reacts with Human, Mouse, Rat, Dog and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: C-QPNVDTRQ KQ. It is sometimes possible for the material contained within the vial of "VPS25, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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