NCBI and Uniprot Product Information
NCBI Description
mediates GTP hydrolysis; plays a role in receptor mediated endocytosis; required for agonist-induced internalization of the epidermal growth factor receptor [RGD, Feb 2006]
Uniprot Description
DYN1: a microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Concentrates within the presynaptic compartment and may participate in specialized neuronal functions such as rapid synaptic vesicle recycling. Part of a protein network that controls nucleation of actin from membranes. Contains one PH domain.
Protein type: Vesicle; EC 3.6.5.5; Motor; Microtubule-binding; Motility/polarity/chemotaxis; Hydrolase
Cellular Component: cytoplasm; Golgi apparatus; membrane coat; microtubule; myelin sheath; photoreceptor inner segment; plasma membrane; protein complex; synapse; synaptic vesicle
Molecular Function: D2 dopamine receptor binding; GTP binding; GTPase activity; identical protein binding; nitric-oxide synthase binding; protein binding; protein C-terminus binding; protein complex binding; protein dimerization activity; protein kinase binding
Biological Process: adult locomotory behavior; endocytosis; endosome organization and biogenesis; G-protein coupled receptor internalization; protein tetramerization; receptor internalization; receptor-mediated endocytosis; sensory perception of sound; synaptic transmission, GABAergic
Research Articles on Dnm1
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Product Notes
The Rat Dnm1 dnm1 (Catalog #AAA2880965) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2880965 ELISA Kit recognizes Rat Dnm1. It is sometimes possible for the material contained within the vial of "Dynamin-1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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