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DNA-dependent protein kinase catalytic subunit (dnapkcs) Recombinant Protein | dnapkcs recombinant protein
Recombinant Dictyostelium discoideum DNA-dependent protein kinase catalytic subunit (dnapkcs), partial
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
DNA-dependent protein kinase catalytic subunit (dnapkcs); Recombinant Dictyostelium discoideum DNA-dependent protein kinase catalytic subunit (dnapkcs); partial; dnapkcs recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
3910-4250aa; Partial
Sequence
ELDYPFLIKGGEDLRLDQRIQQLFGIMNEILKRDTACNKRSLNVTTYQVVPMTSKVGIIEWLNDTKPLREILEEQLAHQLKTPRSNVSISKLESTKYHNDWINSFAKYLKPNSPVGPLYQQMFIHATRDDCAKKLEKQHSKVPENLLQNGIWSLSSSPESYLFIRNSFARSLASFSVCSYVIGIGDRHLENFLISQRDGRLIGIDFGHAFGTATQFLPIPELMPFRLTRQFTSFLRPLDSVGLLNHNMTYTLTALQNQKEILLTTMDVFVKEPLLDWSKLATRLVKEQGKHPKDTKNVWFPKQKIQIAKKKLELVNPAYITLEELSGSVHSGLPYEKALSE
Sequence Length
4250
Species
Dictyostelium discoideum (Slime mold)
Production Note
Special Offer: The E Coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E Colihost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E Coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E Coli host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to [email protected] for more details.
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
SDS-Page
SDS-Page
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46.1 kDa
NCBI Official Full Name
DNA-dependent protein kinase subunit
NCBI Official Symbol
dnapkcs
NCBI Protein Information
DNA-dependent protein kinase subunit; DNAPK subfamily protein kinase; PIKK family protein kinase; phosphatidylinositol 3-kinase-related protein kinase; protein kinase, Atypical group
UniProt Protein Name
DNA-dependent protein kinase catalytic subunit
Protein Family
UniProt Gene Name
dnapkcs
UniProt Synonym Gene Names
DNA-PK catalytic subunit; DNA-PKcs
Uniprot Description
Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Is recruited to DNA ends by the Ku70/Ku80 heterodimer and is involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination (). This activity is only apparent when DNA damage is administered in G1 phase of the cell cycle. Required for efficient signaling of DNA double-stranded breaks via phosphorylation of H2AX during G1.
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Product Notes
The dnapkcs dnapkcs (Catalog #AAA1476938) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 3910-4250aa; Partial. The amino acid sequence is listed below: ELDYPFLIKG GEDLRLDQRI QQLFGIMNEI LKRDTACNKR SLNVTTYQVV PMTSKVGIIE WLNDTKPLRE ILEEQLAHQL KTPRSNVSIS KLESTKYHND WINSFAKYLK PNSPVGPLYQ QMFIHATRDD CAKKLEKQHS KVPENLLQNG IWSLSSSPES YLFIRNSFAR SLASFSVCSY VIGIGDRHLE NFLISQRDGR LIGIDFGHAF GTATQFLPIP ELMPFRLTRQ FTSFLRPLDS VGLLNHNMTY TLTALQNQKE ILLTTMDVFV KEPLLDWSKL ATRLVKEQGK HPKDTKNVWF PKQKIQIAKK KLELVNPAYI TLEELSGSVH SGLPYEKALS E. It is sometimes possible for the material contained within the vial of "DNA-dependent protein kinase catalytic subunit (dnapkcs), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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