Dynein Axonemal Light Chain 4 Recombinant Protein | DNAL4 recombinant protein
Recombinant Human Dynein Axonemal Light Chain 4
Gene Names
DNAL4; MRMV3; PIG27
Purity
Greater than 95% as determined by SDS-PAGE.
Synonyms
Dynein Axonemal Light Chain 4; Recombinant Human Dynein Axonemal Light Chain 4; DNAL4 Human; Dynein Axonemal Light Chain 4 Human Recombinant; Dynein light chain 4 axonemal; DNAL4; PIG27; DNAL4 recombinant protein
Host
E Coli
Purity/Purification
Greater than 95% as determined by SDS-PAGE.
Form/Format
DNAL4 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT.
Sterile Filtered clear solution.
Sterile Filtered clear solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGETEGKKDE ADYKRLQTFP LVRHSDMPEE MRVETMELCV TACEKFSNNN ESAAKMIKET MDKKFGSSWH VVIGEGFGFE ITHEVKNLLY LYFGGTLAVC VWKCS
Sequence Length
105
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Related Product Information for DNAL4 recombinant protein
Description: DNAL4 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 125 amino acids (1-105 a.a) and having a molecular mass of 14.1kDa.DNAL4 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: DNAL4 is a member of the dynein light chain family. DNAL4 is a component of the dynein motor complex in cells that converts the chemical energy contained in ATP into the mechanical energy of movement. Dynein transports various cellular cargos by moving the length of cytoskeletal microtubules towards the minus-end of the microtubule, which is typically oriented towards the cell center.
Introduction: DNAL4 is a member of the dynein light chain family. DNAL4 is a component of the dynein motor complex in cells that converts the chemical energy contained in ATP into the mechanical energy of movement. Dynein transports various cellular cargos by moving the length of cytoskeletal microtubules towards the minus-end of the microtubule, which is typically oriented towards the cell center.
Product Categories/Family for DNAL4 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
12,009 Da
NCBI Official Full Name
dynein light chain 4, axonemal
NCBI Official Synonym Full Names
dynein, axonemal, light chain 4
NCBI Official Symbol
DNAL4
NCBI Official Synonym Symbols
MRMV3; PIG27
NCBI Protein Information
dynein light chain 4, axonemal; dynein light chain, outer arm 4; dynein, axonemal, light polypeptide 4; proliferation-inducing gene 27; proliferation-inducing protein 27
UniProt Protein Name
Dynein light chain 4, axonemal
Protein Family
UniProt Gene Name
DNAL4
UniProt Entry Name
DNAL4_HUMAN
NCBI Description
This gene encodes an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. The encoded protein is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella. [provided by RefSeq, Dec 2014]
Uniprot Description
DNAL4: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity. Belongs to the dynein light chain family.
Chromosomal Location of Human Ortholog: 22q13.1
Cellular Component: dynein complex; microtubule; cytoplasm; plasma membrane; cilium
Molecular Function: motor activity
Biological Process: nerve growth factor receptor signaling pathway; metabolic process; microtubule-based process
Disease: Mirror Movements 3
Research Articles on DNAL4
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Product Notes
The DNAL4 dnal4 (Catalog #AAA145084) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGETEGKKDE ADYKRLQTFP LVRHSDMPEE MRVETMELCV TACEKFSNNN ESAAKMIKET MDKKFGSSWH VVIGEGFGFE ITHEVKNLLY LYFGGTLAVC VWKCS. It is sometimes possible for the material contained within the vial of "Dynein Axonemal Light Chain 4, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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