DnaJ homolog subfamily C member 7 (DNAJC7) Recombinant Protein | DNAJC7 recombinant protein
Recombinant Human DnaJ homolog subfamily C member 7 (DNAJC7)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the DNAJ heat shock protein 40 family of proteins that is characterized by two N-terminal tetratricopeptide repeat domains and a C-terminal DNAJ domain. This protein binds the chaperone proteins heat shock proteins 70 and 90 in an ATP-dependent manner and may function as a co-chaperone. Pseudogenes of this gene are found on chromosomes 1 and 6. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]
Uniprot Description
Acts as co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors, such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. In vitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate complexes. Recruits NR1I3 to the cytoplasm ().
Research Articles on DNAJC7
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Product Notes
The DNAJC7 dnajc7 (Catalog #AAA1285104) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-494, Full length protein. The amino acid sequence is listed below: AAAAECDVVM AATEPELLDD QEAKREAETF KEQGNAYYAK KDYNEAYNYY TKAIDMCPKN ASYYGNRAAT LMMLGRFREA LGDAQQSVRL DDSFVRGHLR EGKCHLSLGN AMAACRSFQR ALELDHKNAQ AQQEFKNANA VMEYEKIAET DFEKRDFRKV VFCMDRALEF APACHRFKIL KAECLAMLGR YPEAQSVASD ILRMDSTNAD ALYVRGLCLY YEDCIEKAVQ FFVQALRMAP DHEKACIACR NAKALKAKKE DGNKAFKEGN YKLAYELYTE ALGIDPNNIK TNAKLYCNRG TVNSKLRKLD DAIEDCTNAV KLDDTYIKAY LRRAQCYMDT EQYEEAVRDY EKVYQTEKTK EHKQLLKNAQ LELKKSKRKD YYKILGVDKN ASEDEIKKAY RKRALMHHPD RHSGASAEVQ KEEEKKFKEV GEAFTILSDP KKKTRYDSGQ DLDEEGMNMG DFDPNNIFKA FFGGPGGFSF EASGPGNFFF QFG. It is sometimes possible for the material contained within the vial of "DnaJ homolog subfamily C member 7 (DNAJC7), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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