Human discs, large homolog 5 (Drosophila) ELISA Kit | DLG5 elisa kit
Human Disks large homolog 5, DLG5 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the family of discs large (DLG) homologs, a subset of the membrane-associated guanylate kinase (MAGUK) superfamily. The MAGUK proteins are composed of a catalytically inactive guanylate kinase domain, in addition to PDZ and SH3 domains, and are thought to function as scaffolding molecules at sites of cell-cell contact. The protein encoded by this gene localizes to the plasma membrane and cytoplasm, and interacts with components of adherens junctions and the cytoskeleton. It is proposed to function in the transmission of extracellular signals to the cytoskeleton and in the maintenance of epithelial cell structure. Alternative splice variants have been described but their biological nature has not been determined. [provided by RefSeq, Jul 2008]
Uniprot Description
DLG5: May play a role at the plasma membrane in the maintenance of the structure of epithelial cells and in the transmission of extracellular signals to the membrane and cytoskeleton. Belongs to the MAGUK family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 10q23
Cellular Component: cell-cell adherens junction; cytoplasm; plasma membrane
Molecular Function: protein binding; receptor signaling complex scaffold activity; cytoskeletal protein binding; beta-catenin binding
Biological Process: regulation of apoptosis; establishment and/or maintenance of epithelial cell polarity; negative regulation of cell proliferation; polarized epithelial cell differentiation; cell-cell adhesion; apical protein localization; midbrain development; zonula adherens assembly; protein complex assembly; signal transduction
Disease: Inflammatory Bowel Disease 1
Research Articles on DLG5
Similar Products
Product Notes
The Human DLG5 dlg5 (Catalog #AAA9317529) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9317529 ELISA Kit recognizes Human DLG5. It is sometimes possible for the material contained within the vial of "discs, large homolog 5 (Drosophila), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
