Disks large homolog 2 (DLG2) Recombinant Protein | DLG2 recombinant protein

Recombinant Human Disks large homolog 2 (DLG2) , partial

• Gene Names: DLG2; PSD93; PSD-93; PPP1R58; chapsyn-110
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Disks large homolog 2 (DLG2); Recombinant Human Disks large homolog 2 (DLG2); partial; DLG2 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 334

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for DLG2 recombinant protein

This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. The encoded protein forms a heterodimer with a related family member that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described, but their full-length nature is not known.

NCBI and Uniprot Product Information

• NCBI GI #: 218156338
• NCBI GeneID: 1740
• NCBI Accession #: NP_001136171.1
• NCBI GenBank Nucleotide #: NM_001142699.1
• UniProt Accession #: Q15700; Q59G57; Q5H9Q4; Q68CQ8; Q6ZTA8; B7WNY8; F8W9V6
• Molecular Weight: 38,404 Da
• NCBI Official Full Name: disks large homolog 2 isoform 1
• NCBI Official Synonym Full Names: discs large MAGUK scaffold protein 2
• NCBI Official Symbol: DLG2
• NCBI Official Synonym Symbols: PSD93; PSD-93; PPP1R58; chapsyn-110
• NCBI Protein Information: disks large homolog 2
• UniProt Protein Name: Disks large homolog 2
• Protein Family: Disks large
• UniProt Gene Name: DLG2
• UniProt Synonym Gene Names: Chapsyn-110

NCBI Description

This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. The encoded protein forms a heterodimer with a related family member that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described, but their full-length nature is not known. [provided by RefSeq, Dec 2008]

Uniprot Description

Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses ().