Human CXCL2 ELISA Kit | CXCL2 elisa kit

Human CXCL2 ELISA Kit

Cat. Num. AAA8291342

• Gene Names: CXCL2; GRO2; GROb; MIP2; MIP2A; SCYB2; MGSA-b; MIP-2a; CINC-2a
• Reactivity: Human
• Synonyms: CXCL2; Human CXCL2 ELISA Kit; GRO2; GROB; MIP2A; SCYB2; C-X-C motif chemokine 2; Growth-regulated protein beta; Gro-beta; Macrophage inflammatory protein 2-alpha; MIP2-alpha; CXCL2 elisa kit

• Reactivity: Human
• Specificity: The Human CXCL2 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human CXCL2 proteins within the range of 15.6 pg/ml - 1000 pg/ml.
• Sequence Length: 107

• Samples: Cell culture supernates, serum, plasma
• Sensitivity: < 7 pg/ml
• Preparation and Storage: Store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for CXCL2 elisa kit

Principle of the Assay: The MyBiosource' Human CXCL2 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Human CXCL2 in Cell Culture Supernates, Serum, Plasma. This assay employs an antibody specific for Human CXCL2 coated on a 96-well plate. Standards and samples are pipetted into the wells and CXCL2 present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Human CXCL2 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of CXCL2 bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm.

Background/Introduction: MIP is a member of the aquaporin family of membrane-bound water channels. MIP family proteins are thought to contain 6 TM domains. Sequence analysis suggests that the proteins may have arisen through tandem, intragenic duplication from an ancestral protein that contained 3 TM domains. Major intrinsic protein (MIP, also called MP26) is the predominant fiber cell membrane protein of the ocular lens. The major intrinsic protein (MIP) of the vertebrate eye lens is the first identified member of a sequence-related family of cell-membrane proteins that appears to have evolved by gene duplication. Several members of the MIP family transport water (aquaporins), glycerol and other small molecules in microbial, plant and animal cells.

NCBI and Uniprot Product Information

• NCBI GI #: 4504155
• NCBI GeneID: 2920
• NCBI Accession #: NP_002080.1
• NCBI GenBank Nucleotide #: NM_002089.3
• UniProt Accession #: P19875; Q6FGD6; Q9UPB8
• Molecular Weight: 11,389 Da
• NCBI Official Full Name: C-X-C motif chemokine 2
• NCBI Official Synonym Full Names: C-X-C motif chemokine ligand 2
• NCBI Official Symbol: CXCL2
• NCBI Official Synonym Symbols: GRO2; GROb; MIP2; MIP2A; SCYB2; MGSA-b; MIP-2a; CINC-2a
• NCBI Protein Information: C-X-C motif chemokine 2
• UniProt Protein Name: C-X-C motif chemokine 2
• Protein Family: C-X-C motif chemokine
• UniProt Gene Name: CXCL2
• UniProt Synonym Gene Names: GRO2; GROB; MIP2A; SCYB2; Gro-beta; MIP2-alpha; HSF

NCBI Description

This antimicrobial gene is part of a chemokine superfamily that encodes secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CXC subfamily, is expressed at sites of inflammation and may suppress hematopoietic progenitor cell proliferation. [provided by RefSeq, Sep 2014]

Uniprot Description

Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.