Human diacylglycerol kinase, eta ELISA Kit | DGKH elisa kit
Human Diacylglycerol kinase eta, DGKH ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the diacylglycerol kinase (DGK) enzyme family. Members of this family are involved in regulating intracellular concentrations of diacylglycerol and phosphatidic acid. Variation in this gene has been associated with bipolar disorder. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Jul 2014]
Uniprot Description
DGKH: Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). Plays a key role in promoting cell growth. Activates the Ras/B-Raf/C-Raf/MEK/ERK signaling pathway induced by EGF. Regulates the recruitment of RAF1 and BRAF from cytoplasm to membranes and their heterodimerization. Belongs to the eukaryotic diacylglycerol kinase family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Lipid Metabolism - glycerolipid; EC 2.7.1.107; Lipid Metabolism - glycerophospholipid; Motility/polarity/chemotaxis; Kinase, other
Chromosomal Location of Human Ortholog: 13q14.11
Cellular Component: nuclear membrane; cytoplasm; plasma membrane; nucleus; endosome
Molecular Function: metal ion binding; diacylglycerol kinase activity; ATP binding; NAD+ kinase activity
Biological Process: platelet activation; protein kinase C activation; blood coagulation; phosphorylation; protein oligomerization
Research Articles on DGKH
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Product Notes
The Human DGKH dgkh (Catalog #AAA9337107) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9337107 ELISA Kit recognizes Human DGKH. It is sometimes possible for the material contained within the vial of "diacylglycerol kinase, eta, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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