Epithelial discoidin domain-containing receptor 1 (DDR1) Recombinant Protein | DDR1 recombinant protein
Recombinant Pan troglodytes Epithelial discoidin domain-containing receptor 1 (DDR1), partial
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Epithelial discoidin domain-containing receptor 1 (DDR1); Recombinant Pan troglodytes Epithelial discoidin domain-containing receptor 1 (DDR1); partial; DDR1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
21-413
Sequence
DMKGHFDPAK CRYALGMQDR TIPDSDISAS SSWSDSTAAR HSSDGDGAWC PAGSVFPKEE EYLQVDLQRL HLVALVGTQG RHAGGLGKEF SRSYRLRYSR DGRRWMGWKD RWGQEVISGN EDPEGVVLKD LGPPMVARLV RFYPRADRVM SVCLRVELYG CLWRDGLLSY TAPVGQTMYL SEAVYLNDST YDGHTVGGLQ YGGLGQLADG VVGLDDFRKS QELRVWPGYD YVGWSNHSFS SGYVEMEFEF DRLRAFQAMQ VHCNNMHTLG ARLPGGVECR FRRGPAMAWE GEPMRHNLGG NLGDPRARAV SVPLGGRVAR FLQCRFLFAG PWLLFSEISF ISDVVNNSSP ALGGTFPPAP WWPPGPPPTN FSSLELEPRG QQPVAKAEGS PTA
Sequence Length
393
Species
Pan troglodytes (Chimpanzee)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
100,642 Da
NCBI Official Full Name
epithelial discoidin domain-containing receptor 1
NCBI Official Synonym Full Names
discoidin domain receptor tyrosine kinase 1
NCBI Official Symbol
DDR1
NCBI Protein Information
epithelial discoidin domain-containing receptor 1
UniProt Protein Name
Epithelial discoidin domain-containing receptor 1
Protein Family
UniProt Gene Name
DDR1
UniProt Synonym Gene Names
EDDR1; Epithelial discoidin domain receptor 1
Uniprot Description
Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing ().
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Product Notes
The DDR1 ddr1 (Catalog #AAA1448053) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 21-413. The amino acid sequence is listed below: DMKGHFDPAK CRYALGMQDR TIPDSDISAS SSWSDSTAAR HSSDGDGAWC PAGSVFPKEE EYLQVDLQRL HLVALVGTQG RHAGGLGKEF SRSYRLRYSR DGRRWMGWKD RWGQEVISGN EDPEGVVLKD LGPPMVARLV RFYPRADRVM SVCLRVELYG CLWRDGLLSY TAPVGQTMYL SEAVYLNDST YDGHTVGGLQ YGGLGQLADG VVGLDDFRKS QELRVWPGYD YVGWSNHSFS SGYVEMEFEF DRLRAFQAMQ VHCNNMHTLG ARLPGGVECR FRRGPAMAWE GEPMRHNLGG NLGDPRARAV SVPLGGRVAR FLQCRFLFAG PWLLFSEISF ISDVVNNSSP ALGGTFPPAP WWPPGPPPTN FSSLELEPRG QQPVAKAEGS PTA. It is sometimes possible for the material contained within the vial of "Epithelial discoidin domain-containing receptor 1 (DDR1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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