Mouse deleted in colorectal carcinoma ELISA Kit | DCC elisa kit
Mouse Netrin receptor DCC, DCC ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
DCC: Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene. Defects in DCC are the cause of mirror movements type 1 (MRMV1). A disorder characterized by contralateral involuntary movements that mirror voluntary ones. While mirror movements are occasionally found in young children, persistence beyond the age of 10 is abnormal. Mirror movements occur more commonly in the upper extremities. Belongs to the immunoglobulin superfamily. DCC family.
Protein type: Receptor, misc.; Immunoglobulin superfamily; Tumor suppressor; Membrane protein, integral
Cellular Component: membrane; axon; integral to membrane; lipid raft
Molecular Function: identical protein binding; protein binding; netrin receptor activity; transcription coactivator activity
Biological Process: axon guidance; spinal cord ventral commissure morphogenesis; apoptosis; multicellular organismal development; neuron migration; dorsal/ventral axon guidance; anterior/posterior axon guidance
Research Articles on DCC
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Product Notes
The Mouse DCC dcc (Catalog #AAA9328108) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9328108 ELISA Kit recognizes Mouse DCC. It is sometimes possible for the material contained within the vial of "deleted in colorectal carcinoma, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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