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C-X-C chemokine receptor type 2 (CXCR2) Recombinant Protein | CXCR2 recombinant protein

Recombinant Rabbit C-X-C chemokine receptor type 2 (CXCR2)

Gene Names
CXCR2; IL8RB
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
C-X-C chemokine receptor type 2 (CXCR2); Recombinant Rabbit C-X-C chemokine receptor type 2 (CXCR2); Recombinant C-X-C chemokine receptor type 2 (CXCR2); C-X-C chemokine receptor type 2; CXC-R2; CXCR-2; GRO/MGSA receptor High affinity interleukin-8 receptor B; IL-8R B CD_antigen= CD182; CXCR2 recombinant protein
Ordering
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-358
Sequence
MQEFTWENYSYEDFFGDFSNYSYSTDLPPTLLDSAPCRSESLETNSYVVLITYILVFLLSLLGNSLVMLVILYSRSTCSVTDVYLLNLAIADLLFATTLPIWAASKVHGWTFGTPLCKVVSLVKEVNFYSGILLLACISVDRYLAIVHATRTMIQKRHLVKFICLSMWGVSLILSLPILLFRNAIFPPNSSPVCYEDMGNSTAKWRMVLRILPQTFGFILPLLVMLFCYVFTLRTLFQAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLTDTLMRTHVIQETCERRNDIDRALDATEILGFLHSCLNPIIYAFIGQKFRYGLLKILAAHGLISKEFLAKESRPSFVASSSGNTSTTL
Sequence Length
358
Species
Oryctolagus cuniculus (Rabbit)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
40,632 Da
NCBI Official Full Name
C-X-C chemokine receptor type 2
NCBI Official Symbol
CXCR2
NCBI Official Synonym Symbols
IL8RB
NCBI Protein Information
C-X-C chemokine receptor type 2; CXC-R2; CXCR-2; IL-8R B; IL-8 receptor; GRO/MGSA receptor; interleukin 8 receptor beta; high affinity interleukin-8 receptor B
UniProt Protein Name
C-X-C chemokine receptor type 2
Protein Family
UniProt Gene Name
CXCR2
UniProt Synonym Gene Names
IL8RB; CXC-R2; CXCR-2; IL-8R B
UniProt Entry Name
CXCR2_RABIT

Uniprot Description

Function: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2

By similarity.

Subcellular location: Cell membrane; Multi-pass membrane protein.

Tissue specificity: Expressed preferentially in neutrophils.

Post-translational modification: Phosphorylated upon ligand binding; which is required for desensitization

By similarity.

Sequence similarities: Belongs to the G-protein coupled receptor 1 family.

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Product Notes

The CXCR2 cxcr2 (Catalog #AAA1208770) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-358. The amino acid sequence is listed below: MQEFTWENYS YEDFFGDFSN YSYSTDLPPT LLDSAPCRSE SLETNSYVVL ITYILVFLLS LLGNSLVMLV ILYSRSTCSV TDVYLLNLAI ADLLFATTLP IWAASKVHGW TFGTPLCKVV SLVKEVNFYS GILLLACISV DRYLAIVHAT RTMIQKRHLV KFICLSMWGV SLILSLPILL FRNAIFPPNS SPVCYEDMGN STAKWRMVLR ILPQTFGFIL PLLVMLFCYV FTLRTLFQAH MGQKHRAMRV IFAVVLIFLL CWLPYNLVLL TDTLMRTHVI QETCERRNDI DRALDATEIL GFLHSCLNPI IYAFIGQKFR YGLLKILAAH GLISKEFLAK ESRPSFVASS SGNTSTTL. It is sometimes possible for the material contained within the vial of "C-X-C chemokine receptor type 2 (CXCR2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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