Granulocyte Chemotactic Protein 2 (GCP2) Recombinant Protein | GCP2 recombinant protein

Recombinant Granulocyte Chemotactic Protein 2 (GCP2)

Cat. Num. AAA2010922

• Gene Names: CXCL6; GCP2; CKA-3; GCP-2; SCYB6
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: > 95%
• Synonyms: Granulocyte Chemotactic Protein 2 (GCP2); Recombinant Granulocyte Chemotactic Protein 2 (GCP2); GCP2 recombinant protein

• Host: E Coli
• Purity/Purification: > 95%
• Form/Format: Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Sequence: The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.; MGSSHHHHHHSSGLVPRGSHMASMTGGQQMGRGS-VSAV LTELRCTCLR VTLRVNPKTI GKLQVFPAGP QCSKVEVVAS LKNGKQVCLDPEAPFLKKVI QKILDSGNKK N
• Sequence Length: 114

• Applicable Applications for GCP2 recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Organism: Homo sapiens (Human)
• Expression System: Prokaryotic expression
• Residues: Val40~Asn114 (Accession # P80162) with two N-terminal Tags, His-tag and T7-tag
• Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 4506851
• NCBI GeneID: 6372
• NCBI Accession #: NP_002984.1
• NCBI GenBank Nucleotide #: NM_002993.3
• UniProt Accession #: P80162; Q4W5D4; B2R4X3
• Molecular Weight: 11.7kDa
• NCBI Official Full Name: C-X-C motif chemokine 6
• NCBI Official Synonym Full Names: chemokine (C-X-C motif) ligand 6
• NCBI Official Symbol: CXCL6
• NCBI Official Synonym Symbols: GCP2; CKA-3; GCP-2; SCYB6
• NCBI Protein Information: C-X-C motif chemokine 6; chemokine alpha 3; small-inducible cytokine B6; granulocyte chemotactic protein 2; Small inducible cytokine subfamily B (Cys-X-Cys), member b; chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2); small inducible cytokine subfamily B (Cys-X-Cys), member 6 (granulocyte chemotactic protein 2)
• UniProt Protein Name: C-X-C motif chemokine 6
• Protein Family: Gamma-tubulin complex component
• UniProt Gene Name: CXCL6
• UniProt Synonym Gene Names: GCP2; SCYB6; CKA-3; GCP-2
• UniProt Entry Name: CXCL6_HUMAN

Uniprot Description

CXCL6: Chemotactic for neutrophil granulocytes. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: extracellular space; extracellular region

Molecular Function: heparin binding; chemokine activity; CXCR chemokine receptor binding

Biological Process: G-protein coupled receptor protein signaling pathway; cell-cell signaling; defense response to bacterium; neutrophil mediated immunity; response to lipopolysaccharide; immune response; positive regulation of leukocyte chemotaxis; signal transduction; inflammatory response; chemotaxis; regulation of cell proliferation