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C-X-C Motif Chemokine 6/CXCL6 Recombinant Protein | C-X-C recombinant protein
Recombinant Human C-X-C Motif Chemokine 6/CXCL6 (C-6His)
Gene Names
CXCL6; GCP2; CKA-3; GCP-2; SCYB6
Purity
>95% as determined by reducing SDS-PAGE
Synonyms
C-X-C Motif Chemokine 6/CXCL6; Recombinant Human C-X-C Motif Chemokine 6/CXCL6 (C-6His); C-X-C Motif Chemokine 6; Chemokine Alpha 3; CKA-3; Granulocyte Chemotactic Protein 2; GCP-2; Small-Inducible Cytokine B6; CXCL6; GCP2; SCYB6; C-X-C recombinant protein
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE
Form/Format
Lyophilized from a 0.2um filtered solution of 20mM PB, 150mM NaCl, 5% Trehalose, pH7.4.
Sequence
Gly38-Asn114
Species
Human
Tag
C-6His
Endotoxin
<1.0EU per ug as determined by the LAL method.
Protein Construction
Recombinant Human C-X-C Motif Chemokine 6 is produced by our Mammalian expression system and the target gene encoding Gly38-Asn114 is expressed with a 6His tag at the C-terminus.
Preparation and Storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 degree C. Reconstituted protein solution can be stored at 4-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
This product is provided as lyophilized powder which is shipped with ice packs.
This product is provided as lyophilized powder which is shipped with ice packs.
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Related Product Information for C-X-C recombinant protein
Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. It is a potent neutrophil chemotactic and activating factor and it exhibits extensive similarity to other CXC chemokines such as IL-8 and ENA-78. CXCL6 can promote the release of MMP-9 from granulocytes indicating its potential role as an inflammatory mediator. It functionally uses both of the IL-8/CXCL8 receptors to chemoattract neutrophils but that is structurally most related to epithelial cell-derived neutrophil attractant-78 (ENA-78)/CXCL5. The human CXCL6 gene has been cloned and is physically mapped to the CXC chemokine locus on chromosome 4. Mature human CXCL6 is a 75 amino acid (aa) protein with a predicted molecular weight of approximately 8kDa. Human CXCL6 shares 60% and 67% aa identity with mouse and bovine CXCL6, respectively.
Product Categories/Family for C-X-C recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
11,897 Da
NCBI Official Full Name
C-X-C motif chemokine 6
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 6
NCBI Official Symbol
CXCL6
NCBI Official Synonym Symbols
GCP2; CKA-3; GCP-2; SCYB6
NCBI Protein Information
C-X-C motif chemokine 6; Small inducible cytokine subfamily B (Cys-X-Cys), member b; chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2); chemokine alpha 3; small inducible cytokine subfamily B (Cys-X-Cys), member 6 (granulocyte chemotact
UniProt Protein Name
C-X-C motif chemokine 6
UniProt Gene Name
CXCL6
UniProt Synonym Gene Names
GCP2; SCYB6; CKA-3; GCP-2
UniProt Entry Name
CXCL6_HUMAN
Uniprot Description
CXCL6: Chemotactic for neutrophil granulocytes. Belongs to the intercrine alpha (chemokine CxC) family.
Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted
Chromosomal Location of Human Ortholog: 4q13.3
Cellular Component: extracellular space; extracellular region
Molecular Function: heparin binding; chemokine activity; CXCR chemokine receptor binding
Biological Process: G-protein coupled receptor protein signaling pathway; cell-cell signaling; defense response to bacterium; neutrophil mediated immunity; response to lipopolysaccharide; positive regulation of leukocyte chemotaxis; immune response; chemotaxis; signal transduction; inflammatory response; regulation of cell proliferation
Research Articles on C-X-C
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Product Notes
The C-X-C cxcl6 (Catalog #AAA2569084) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Gly38-Asn1 14. It is sometimes possible for the material contained within the vial of "C-X-C Motif Chemokine 6/CXCL6, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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