Typical Testing Data/Standard Curve
Rat GRO gamma ELISA Kit | CXCL3 elisa kit
Rat GRO gamma ELISA Kit
Gene Names
Cxcl3; Cinc2; Cinc-2; Gm1960
Reactivity
Rat
Applications
ELISA
Synonyms
GRO gamma; Rat GRO gamma ELISA Kit; GRO3; GROG; SCYB3; C-X-C motif chemokine 3; GRO-gamma(1-73); Growth-regulated protein gamma; GRO-gamma; Macrophage inflammatory protein 2-beta; MIP2-beta; CXCL3 elisa kit
Reactivity
Rat
Specificity
The Rat GRO gamma ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Rat GRO gamma proteins within the range of 15.6 pg/ml - 1000 pg/ml.
Sequence Length
101
Applicable Applications for CXCL3 elisa kit
Sandwich ELISA (EIA)
Samples
Cell Culture Supernatants, Serum, Plasma.
Sensitivity
10 pg/ml.
Preparation and Storage
Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
Typical Testing Data/Standard Curve
Typical Testing Data/Standard Curve
Related Product Information for CXCL3 elisa kit
Principle of the Assay||The Rat GRO gamma ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Rat GRO gamma in Cell Culture Supernatants, Serum, Plasma. This assay employs an antibody specific for Rat GRO gamma coated on a 96-well plate. Standards and samples are pipetted into the wells and GRO gamma present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Rat GRO gamma antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of GRO gamma bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm.
Background/Introduction: Chemokine (C-X-C motif) ligand 3 (CXCL3) is a small cytokine belonging to the CXC chemokine family. It is mapped to 14p2 in rat. CXCL3 controls migration and adhesion of monocytes and mediates its effects on its target cell by interacting with a cell surface chemokine receptor. It has been shown that CXCL3 regulates cell autonomously the migration of the precursors of cerebellar granule neurons toward the internal layers of cerebellum, during the morphogenesis of cerebellum. CXCL3 also play fundamental roles in the development, homeostasis and it has effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.
Background/Introduction: Chemokine (C-X-C motif) ligand 3 (CXCL3) is a small cytokine belonging to the CXC chemokine family. It is mapped to 14p2 in rat. CXCL3 controls migration and adhesion of monocytes and mediates its effects on its target cell by interacting with a cell surface chemokine receptor. It has been shown that CXCL3 regulates cell autonomously the migration of the precursors of cerebellar granule neurons toward the internal layers of cerebellum, during the morphogenesis of cerebellum. CXCL3 also play fundamental roles in the development, homeostasis and it has effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
10,989 Da
NCBI Official Full Name
C-X-C motif chemokine 3
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 3
NCBI Official Symbol
Cxcl3
NCBI Official Synonym Symbols
Cinc2; Cinc-2; Gm1960
NCBI Protein Information
C-X-C motif chemokine 3
UniProt Protein Name
C-X-C motif chemokine 3
Protein Family
UniProt Gene Name
Cxcl3
UniProt Synonym Gene Names
Cinc2; CINC-2; MIP2-alpha/beta
UniProt Entry Name
CXCL3_RAT
NCBI Description
acts as a chemoattractant for neutrophils; involved in the inflammatory response [RGD, Feb 2006]
Uniprot Description
CXCL1: Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO- alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity. Belongs to the intercrine alpha (chemokine CxC) family.
Protein type: Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted
Cellular Component: cytosol; extracellular space
Molecular Function: chemokine activity; CXCR chemokine receptor binding
Biological Process: elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; immune response; inflammatory response; neutrophil chemotaxis; regulation of cell proliferation; response to lipopolysaccharide
Research Articles on CXCL3
Similar Products
Product Notes
The Rat CXCL3 cxcl3 (Catalog #AAA8244725) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA8244725 ELISA Kit recognizes Rat CXCL3. AAA Biotech's GRO gamma can be used in a range of immunoassay formats including, but not limited to, Sandwich ELISA (EIA). Researchers should empirically determine the suitability of the CXCL3 cxcl3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GRO gamma, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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