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CXCL13 recombinant protein

RECOMBINANT MOUSE CXCL13

Gene Names
Cxcl13; BLC; Angie; BCA-1; BLR1L; ANGIE2; Scyb13; 4631412M08Rik
Applications
Functional Assay
Purity
>99% by SDS PAGE and HPLC analysis
Synonyms
CXCL13; RECOMBINANT MOUSE CXCL13; CXCL13 recombinant protein
Ordering
For Research Use Only!
Purity/Purification
>99% by SDS PAGE and HPLC analysis
Form/Format
Purified Recombinant Protein - lyophilised
Concentration
Approximate Protein Concentration: 1.0 mg/ml (varies by lot)
Sequence Length
109
Applicable Applications for CXCL13 recombinant protein
Functional Assays (FN)
Reconstitution
Reconstitute with 20 ul distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. MyBioSource recommends that the vial is gently mixed after reconstitution.
Preparation
Target Species
Mouse
Preparation and Storage
Prior to reconstitution store at 4 degree C. Following reconstitution store at -20 degree C. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 3 months from date of reconstitution.
Related Product Information for CXCL13 recombinant protein
Mouse B lymphocyte chemoattractant (BLC) is a 9.5kD chemokine, also known CXCL13. BLC is strongly expressed in the spleen, lymph nodes and Peyers Patches. BLC is chemotactic for B lymphocytes.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
11,927 Da
NCBI Official Full Name
C-X-C motif chemokine 13
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 13
NCBI Official Symbol
Cxcl13
NCBI Official Synonym Symbols
BLC; Angie; BCA-1; BLR1L; ANGIE2; Scyb13; 4631412M08Rik
NCBI Protein Information
C-X-C motif chemokine 13; B lymphocyte chemoattractant; CXC chemokine BLC; small inducible cytokine subfamily B (Cys-X-Cys), member 13; small-inducible cytokine B13
UniProt Protein Name
C-X-C motif chemokine 13
Protein Family
UniProt Gene Name
Cxcl13
UniProt Synonym Gene Names
Blc; Scyb13
UniProt Entry Name
CXL13_MOUSE

Uniprot Description

CXCL13: Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B- lymphocytes. Binds to BLR1/CXCR5. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide

Cellular Component: extracellular space; cell; extracellular region; cytosol

Molecular Function: heparin binding; fibroblast growth factor binding; CXCR3 chemokine receptor binding; chemokine activity; protein heterodimerization activity; CCR10 chemokine receptor binding; CXCR5 chemokine receptor binding; cytokine activity; receptor agonist activity

Biological Process: lymphocyte chemotaxis across high endothelial venule; positive regulation of leukocyte chemotaxis; response to lipopolysaccharide; chemotaxis; positive regulation of integrin activation; positive regulation of cell-cell adhesion mediated by integrin; lymph node development; regulation of cell proliferation; G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; cell surface receptor linked signal transduction; cell-cell signaling; defense response to bacterium; immune response; inflammatory response

Research Articles on CXCL13

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Product Notes

The CXCL13 cxcl13 (Catalog #AAA232348) is a Recombinant Protein and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CXCL13 can be used in a range of immunoassay formats including, but not limited to, Functional Assays (FN). Researchers should empirically determine the suitability of the CXCL13 cxcl13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CXCL13, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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