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Testing Data

Rabbit anti-Human BLC Polyclonal Antibody | anti-BLC antibody

BLC Antibody

Gene Names
Cxcl13; BLC; Angie; BCA-1; BLR1L; ANGIE2; Scyb13; 4631412M08Rik
Reactivity
Human
Applications
Western Blot
Purity
Affinity purified
Synonyms
BLC; Polyclonal Antibody; BLC Antibody; B-lymphocyte chemoattractant; anti-BLC antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
100 ug (0.5 mg/ml) Protein A purified rabbit anti-BLC polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
Appearance: Colorless liquid
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
109
Applicable Applications for anti-BLC antibody
Western Blot (WB)
Application Notes
Western blot (at 0.5-4 ug/ml). However, the optimal conditions should be determined individually.
Immunogen
E. coli expressed recombinant mouse BLC
Handling
The antibody solution should be gently mixed before use.
Preparation and Storage
At -20 degree C
Shelf Life: 12 months

Testing Data

Testing Data
Related Product Information for anti-BLC antibody
Background: BLC (B-lymphocyte chemoattractant) is a 12 kDa ELR-CXC chemokine. BLC showed high levels of expression in spleen, Peyer's patches, and mesenteric lymph nodes. BLC is reported as the ligand of CXCR5. It attracts primarily B cells in vitro. Cell lines transfected with CXCR5 demonstrate both chemotaxis and calcium flux in response to BLC.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
11,927 Da
NCBI Official Full Name
C-X-C motif chemokine 13
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 13
NCBI Official Symbol
Cxcl13
NCBI Official Synonym Symbols
BLC; Angie; BCA-1; BLR1L; ANGIE2; Scyb13; 4631412M08Rik
NCBI Protein Information
C-X-C motif chemokine 13
UniProt Protein Name
C-X-C motif chemokine 13
UniProt Gene Name
Cxcl13
UniProt Synonym Gene Names
Blc; Scyb13
UniProt Entry Name
CXL13_MOUSE

Uniprot Description

CXCL13: Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B- lymphocytes. Binds to BLR1/CXCR5. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Cellular Component: extracellular space; cell; extracellular region; cytosol

Molecular Function: heparin binding; CXCR3 chemokine receptor binding; fibroblast growth factor binding; chemokine activity; protein heterodimerization activity; CXCR5 chemokine receptor binding; CCR10 chemokine receptor binding; cytokine activity; receptor agonist activity

Biological Process: lymphocyte chemotaxis across high endothelial venule; positive regulation of leukocyte chemotaxis; response to lipopolysaccharide; chemotaxis; positive regulation of integrin activation; positive regulation of cell-cell adhesion mediated by integrin; lymph node development; regulation of cell proliferation; G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; cell surface receptor linked signal transduction; cell-cell signaling; defense response to bacterium; immune response; inflammatory response

Research Articles on BLC

Similar Products

Product Notes

The BLC cxcl13 (Catalog #AAA841217) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BLC Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BLC can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blot (at 0.5-4 ug/ml). However, the optimal conditions should be determined individually. Researchers should empirically determine the suitability of the BLC cxcl13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BLC, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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