Fractalkine (Cx3cl1) Recombinant Protein | Cx3cl1 recombinant protein

Recombinant Mouse Fractalkine (Cx3cl1)

• Gene Names: Cx3cl1; CX3C; Cxc3; Scyd1; ABCD-3; AB030188; AI848747; D8Bwg0439e
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Fractalkine (Cx3cl1); Recombinant Mouse Fractalkine (Cx3cl1); Fractalkine; C-X3-C motif chemokine 1; CX3C membrane-anchored chemokine; Neurotactin; Small-inducible cytokine D1Cleaved into the following chain:; 1. Processed fractalkine; Cx3cl1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 25-336
• Sequence: QHLGMT KCEIMCDKMT SRIPVALLIR YQLNQESCGK RAIVLETTQH RRFCADPKEK WVQDAMKHLD HQAAALTKNG GKFEKRVDNV TPGITLATRG LSPSALTKPE SATLEDLALE LTTISQEARG TMGTSQEPPA AVTGSSLSTS EAQDAGLTAK PQSIGSFEAA DISTTVWPSP AVYQSGSSSW AEEKATESPS TTAPSPQVST TSPSTPEENV GSEGQPPWVQ GQDLSPEKSL GSEEINPVHT DNFQERGPGN TVHPSVAPIS SEETPSPELV ASGSQAPKIE EPIHATADPQ KLSVLITPVP DTQAAT
• Sequence Length: 312

• Species: Mus musculus (Mouse)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 31982017
• NCBI GeneID: 20312
• NCBI Accession #: NP_033168.2
• NCBI GenBank Nucleotide #: NM_009142.3
• UniProt Accession #: O35188; O35933; Q91V44
• Molecular Weight: 42,099 Da
• NCBI Official Full Name: fractalkine
• NCBI Official Synonym Full Names: chemokine (C-X3-C motif) ligand 1
• NCBI Official Symbol: Cx3cl1
• NCBI Official Synonym Symbols: CX3C; Cxc3; Scyd1; ABCD-3; AB030188; AI848747; D8Bwg0439e
• NCBI Protein Information: fractalkine; neurotactin; C-X3-C motif chemokine 1; small-inducible cytokine D1; CX3C membrane-anchored chemokine; small inducible cytokine subfamily D, 1
• UniProt Protein Name: Fractalkine
• Protein Family: Fractalkine
• UniProt Gene Name: Cx3cl1
• UniProt Synonym Gene Names: Cx3c; Fkn; Scyd1
• UniProt Entry Name: X3CL1_MOUSE

Uniprot Description

CX3CL1: The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1. Belongs to the intercrine delta family.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral

Cellular Component: extracellular space; cell projection; cell surface; membrane; perinuclear region of cytoplasm; cytoplasm; plasma membrane; integral to membrane; extracellular region

Molecular Function: chemokine activity; cytokine activity

Biological Process: platelet activation; positive regulation of neuroblast proliferation; neutrophil chemotaxis; positive regulation of transforming growth factor-beta1 production; positive regulation of cell adhesion; wound healing; positive regulation of smooth muscle cell proliferation; cytokine and chemokine mediated signaling pathway; negative regulation of cytokine secretion; microglial cell activation; angiogenesis involved in wound healing; chemotaxis; macrophage chemotaxis; leukocyte adhesive activation; negative regulation of vasoconstriction; regulation of inhibitory postsynaptic membrane potential; positive regulation of angiogenesis; positive regulation of calcium-independent cell-cell adhesion; immune response; cell adhesion; lymphocyte chemotaxis; positive regulation of cell migration