SDS-Page
Colony Stimulating Factor 2 Receptor Alpha (CSF2Ra) Recombinant Protein | CSF2Ra recombinant protein
Recombinant Colony Stimulating Factor 2 Receptor Alpha (CSF2Ra)
Gene Names
Csf2ra; CD116; Csfgmra; GM-CSFR; GM-CSF-Ra
Applications
SDS-Page, Western Blot, ELISA, Immunoprecipitation
Purity
> 95%
Synonyms
Colony Stimulating Factor 2 Receptor Alpha (CSF2Ra); Recombinant Colony Stimulating Factor 2 Receptor Alpha (CSF2Ra); CSF2Ra recombinant protein
Host
E Coli
Purity/Purification
> 95%
Form/Format
Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Sequence
The target protein is fused with N-terminal His-Tag, its sequence is listed below.
MGHHHHHHSGSEF-LDVNGTVG GAAAHWRLSF VNEGAAGSGA ENLTCEIRAA RFLSCAWREG PAAPADVRYS LRVLNSTGHD VARCMADPGD DVITQCIAND LSLLGSEAYL VVTGRSGAGP VRFLDDVVAT KALERLGPPR DVTASCNSSH CTVSWAPPST WASLTARDFQ FEVQ
MGHHHHHHSGSEF-LDVNGTVG GAAAHWRLSF VNEGAAGSGA ENLTCEIRAA RFLSCAWREG PAAPADVRYS LRVLNSTGHD VARCMADPGD DVITQCIAND LSLLGSEAYL VVTGRSGAGP VRFLDDVVAT KALERLGPPR DVTASCNSSH CTVSWAPPST WASLTARDFQ FEVQ
Sequence Length
388
Applicable Applications for CSF2Ra recombinant protein
SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
Organism
Mus musculus (Mouse)
Expression System
Prokaryotic expression
Residues
Leu103~Gln264 (Accession # Q00941) with N-terminal His-Tag
Subcellular Location
Membrane; Single-pass type I membrane protein
Endotoxin Level
<1.0EU per 1ug (determined by the LAL method)
Predicted Isoelectric Point
5.8
Reconstitution
Reconstitute in sterile PBS, pH7.2-pH7.4.
Preparation and Storage
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
SDS-Page
SDS-Page
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
18.6kDa
NCBI Official Full Name
granulocyte-macrophage colony-stimulating factor receptor subunit alpha
NCBI Official Synonym Full Names
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
NCBI Official Symbol
Csf2ra
NCBI Official Synonym Symbols
CD116; Csfgmra; GM-CSFR; GM-CSF-Ra
NCBI Protein Information
granulocyte-macrophage colony-stimulating factor receptor subunit alpha; GMR-alpha; GM-CSFRalpha; GMCSFR-alpha; GM-CSF-R-alpha; colony stimulating factor 2 receptor alpha chain
UniProt Protein Name
Granulocyte-macrophage colony-stimulating factor receptor subunit alpha
Protein Family
UniProt Gene Name
Csf2ra
UniProt Synonym Gene Names
Csfgmra; GM-CSF-R-alpha; GMCSFR-alpha; GMR-alpha
UniProt Entry Name
CSF2R_MOUSE
Uniprot Description
CSF2RA: Low affinity receptor for granulocyte-macrophage colony- stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Defects in CSF2RA are the cause of pulmonary surfactant metabolism dysfunction type 4 (SMDP4). A rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress. Belongs to the type I cytokine receptor family. Type 5 subfamily. 8 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Receptor, cytokine
Cellular Component: membrane; integral to membrane
Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity
Disease: Surfactant Metabolism Dysfunction, Pulmonary, 4
Research Articles on CSF2Ra
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Product Notes
The CSF2Ra csf2ra (Catalog #AAA2010215) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Colony Stimulating Factor 2 Receptor Alpha (CSF2Ra) can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the CSF2Ra csf2ra for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: The target protein is fused with N-terminal His-Tag, its sequence is listed below. MGHHHHHHSG SEF-LDVNGT VG GAAAHWRLSF VNEGAAGSGA ENLTCEIRAA RFLSCAWREG PAAPADVRYS LRVLNSTGHD VARCMADPGD DVITQCIAND LSLLGSEAYL VVTGRSGAGP VRFLDDVVAT KALERLGPPR DVTASCNSSH CTVSWAPPST WASLTARDFQ FEVQ. It is sometimes possible for the material contained within the vial of "Colony Stimulating Factor 2 Receptor Alpha (CSF2Ra), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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