Cyclic AMP-responsive element-binding protein 1 (Creb1) Recombinant Protein | Creb1 recombinant protein

Recombinant Rat Cyclic AMP-responsive element-binding protein 1 (Creb1)

Gene Names

Creb1; Creb

Purity

Greater or equal to 85% purity as determined by SDS-PAGE.

Synonyms

Cyclic AMP-responsive element-binding protein 1 (Creb1); Recombinant Rat Cyclic AMP-responsive element-binding protein 1 (Creb1); Creb1 recombinant protein

Ordering
Cat. Num. AAA961109 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE.

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Sequence Positions

1-341, Full length protein

Sequence

MTMDSGADNQQSGDAAVTEAESQQMTVQAQPQIATLAQVSMPAAHATSSAPTVTLVQLPNGQTVQVHGVIQAAQPSVIQSPQVQTVQSSCKDLKRLFSGTQISTIAESEDSQESVDSVTDSQKRREILSRRPSYRKILNDLSSDAPGVPRIEEEKSEEETSAPAITTVTVPTPIYQTSSGQYIAITQGGAIQLANNGTDGVQGLQTLTMTNAAATQPGTTILQYAQTTDGQQILVPSNQVVVQAASGDVQTYQIRTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSD

Sequence Length

341

Species

Rat

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for Creb1 recombinant protein

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.

NCBI and Uniprot Product Information

NCBI GI #

13591924

NCBI GeneID

81646

NCBI Accession #

NP_112279.1

NCBI GenBank Nucleotide #

NM_031017.1

UniProt Accession #

P15337

Molecular Weight

35,081 Da

NCBI Official Full Name

cyclic AMP-responsive element-binding protein 1 isoform B

NCBI Official Synonym Full Names

cAMP responsive element binding protein 1

NCBI Official Symbol

Creb1

NCBI Official Synonym Symbols

Creb

NCBI Protein Information

cyclic AMP-responsive element-binding protein 1

UniProt Protein Name

Cyclic AMP-responsive element-binding protein 1

Protein Family

Cyclic AMP-responsive element-binding protein

UniProt Gene Name

Creb1

UniProt Synonym Gene Names

Creb-1; CREB-1; cAMP-responsive element-binding protein 1

NCBI Description

binds the cAMP response element in many gene promoters and regulates transcription [RGD, Feb 2006]

Uniprot Description

Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells ().

Research Articles on Creb1

1. CREB overexpression in aged animals ameliorated the long-term memory deficits observed in control animals.

Similar Products

CREB1 Antibody

Host: Rabbit

Reactivity: Human, Mouse, Rat

Apps: ELISA, Western Blot

Product Notes

The Creb1 creb1 (Catalog #AAA961109) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-341, Full length protein. The amino acid sequence is listed below: MTMDSGADNQ QSGDAAVTEA ESQQMTVQAQ PQIATLAQVS MPAAHATSSA PTVTLVQLPN GQTVQVHGVI QAAQPSVIQS PQVQTVQSSC KDLKRLFSGT QISTIAESED SQESVDSVTD SQKRREILSR RPSYRKILND LSSDAPGVPR IEEEKSEEET SAPAITTVTV PTPIYQTSSG QYIAITQGGA IQLANNGTDG VQGLQTLTMT NAAATQPGTT ILQYAQTTDG QQILVPSNQV VVQAASGDVQ TYQIRTAPTS TIAPGVVMAS SPALPTQPAE EAARKREVRL MKNREAAREC RRKKKEYVKC LENRVAVLEN QNKTLIEELK ALKDLYCHKS D. It is sometimes possible for the material contained within the vial of "Cyclic AMP-responsive element-binding protein 1 (Creb1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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