RBM20 (aa717-727) Blocking Peptide | RBM20 blocking peptide

RBM20 (aa717-727) Immunizing Peptide

Cat. Num. AAA427588

• Reactivity: Tested: Mouse; Expected: Human, Rat, Cow
• Synonyms: RBM20 (aa717-727); RBM20 (aa717-727) Immunizing Peptide; Goat Anti-RBM20 (aa671-681) Antibody; RNA binding motif protein 20 antibody; RBM20 antibody; RBM20 blocking peptide

• Reactivity: Tested: Mouse; Expected: Human, Rat, Cow
• Form/Format: 100ug of dried peptide
• Sequence Positions: 717-727
• Sequence: C-PRQLDKAELDE
• Sequence Length: 11

• Corresponding Antibody: The peptide was used in the production of MBS422508 -
• Preparation and Storage: Shipped at ambient temperature, store at -20 degree C.

NCBI and Uniprot Product Information

• NCBI GI #: 197276594
• NCBI GeneID: 282996
• NCBI Accession #: NP_001127835.1
• NCBI GenBank Nucleotide #: NM_001134363.1
• UniProt Accession #: Q5T481; Q5JVI1; A6NIP5; B5A868
• Molecular Weight: 134,357 Da
• NCBI Official Full Name: RNA-binding protein 20
• NCBI Official Synonym Full Names: RNA binding motif protein 20
• NCBI Official Symbol: RBM20
• NCBI Protein Information: RNA-binding protein 20; RNA-binding motif protein 20; probable RNA-binding protein 20
• UniProt Protein Name: RNA-binding protein 20
• Protein Family: RNA-binding protein
• UniProt Gene Name: RBM20
• UniProt Entry Name: RBM20_HUMAN

NCBI Description

This gene encodes a protein that likely binds RNA. Mutations in this gene have been associated with familial dilated cardiomyopathy. [provided by RefSeq, Mar 2010]

Uniprot Description

Function: RNA-binding protein that acts as a regulator of mRNA splicing of a subset of genes involved in cardiac development. Regulates splicing of TTN (Titin). Ref.1

Subcellular location: Nucleus

By similarity.

Tissue specificity: Expressed in the heart. Ref.3

Involvement in disease: Cardiomyopathy, dilated 1DD (CMD1DD) [MIM:613172]: A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.1 Ref.3 Ref.4 Ref.5

Sequence similarities: Contains 1 RRM (RNA recognition motif) domain.

Sequence caution: The sequence CAI16577.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAI40091.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAI40093.1 differs from that shown. Reason: Erroneous gene model prediction.