GIPC1 / NIP Blocking Peptide | GIPC1 blocking peptide
GIPC1 / NIP Immunizing Peptide
NCBI and Uniprot Product Information
NCBI Description
GIPC1 is a scaffolding protein that regulates cell surface receptor expression and trafficking (Lee et al., 2008 [PubMed 18775991]).[supplied by OMIM, Apr 2009]
Uniprot Description
GIPC1: May be involved in G protein-linked signaling. Belongs to the GIPC family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: GAPs; GAPs, misc.; Vesicle; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 19p13.1
Cellular Component: brush border; cell cortex; cytoplasm; cytoplasmic membrane-bound vesicle; cytosol; dendritic shaft; dendritic spine; endocytic vesicle; membrane; synaptic vesicle; vesicle membrane
Molecular Function: actin binding; myosin binding; PDZ domain binding; protein binding; protein homodimerization activity; receptor binding
Biological Process: endothelial cell migration; G-protein coupled receptor protein signaling pathway; glutamate secretion; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of cytokinesis; positive regulation of transforming growth factor beta receptor signaling pathway; protein targeting; regulation of protein stability; regulation of synaptic plasticity; synaptic transmission
Research Articles on GIPC1
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Product Notes
The GIPC1 gipc1 (Catalog #AAA426031) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The GIPC1 / NIP Immunizing Peptide reacts with Human, Mouse, Rat, Cow and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: C-GAIGDAKV GRY. It is sometimes possible for the material contained within the vial of "GIPC1 / NIP, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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