CD19 blocking peptide
CD19 Immunizing Peptide
NCBI and Uniprot Product Information
NCBI Description
Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. [provided by RefSeq, Jul 2008]
Uniprot Description
CD19: a cell surface molecule which assembles with the antigen receptor of B lymphocytes. A critical signal transduction molecule that regulates B lymphocyte development, activation, and differentiation. Ligation increases intracellular calcium levels and decreases the threshold for antigen receptor signaling. Germinal center formation is significantly reduced in CD19-deficient mice.
Protein type: Membrane protein, integral; Cell surface
Chromosomal Location of Human Ortholog: 16p11.2
Cellular Component: external side of plasma membrane; integral to plasma membrane; intracellular; plasma membrane; protein complex
Molecular Function: phosphatidylinositol-4,5-bisphosphate 3-kinase activity; protein binding; receptor signaling protein activity
Biological Process: B cell receptor signaling pathway; cell surface receptor linked signal transduction; cellular defense response; phosphoinositide phosphorylation; phosphoinositide-mediated signaling; regulation of immune response; regulation of phosphoinositide 3-kinase cascade
Disease: Immunodeficiency, Common Variable, 2; Immunodeficiency, Common Variable, 3
Research Articles on CD19
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Product Notes
The CD19 cd19 (Catalog #AAA427864) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The CD19 Immunizing Peptide reacts with Human, Cow and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: C-ENDSNLGQ DQLS. It is sometimes possible for the material contained within the vial of "CD19, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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