IKZF4 blocking peptide
IKZF4 Immunizing Peptide
NCBI and Uniprot Product Information
NCBI Description
Members of the Ikaros (ZNFN1A1; MIM 603023) family of transcription factors, which includes Eos, are expressed in lymphocytes and are implicated in the control of lymphoid development.[supplied by OMIM, Jul 2002]
Uniprot Description
IKZF4: DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence. Transcriptional repressor. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems. Belongs to the Ikaros C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding; C2H2-type zinc finger protein; Transcription factor
Chromosomal Location of Human Ortholog: 12q13
Cellular Component: centrosome; nucleoplasm; nucleus
Molecular Function: bHLH transcription factor binding; metal ion binding; protein heterodimerization activity; protein homodimerization activity; sequence-specific DNA binding; transcription factor activity
Biological Process: negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent
Research Articles on IKZF4
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Product Notes
The IKZF4 ikzf4 (Catalog #AAA425879) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The IKZF4 Immunizing Peptide reacts with Human, Mouse, Dog, Cow and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: C-RPTFIDRL ANSLTKR. It is sometimes possible for the material contained within the vial of "IKZF4, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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