COVID 19 S Protein HR1 (N-6His-Sumo) Coronavirus Recombinant Protein | COVID-19 recombinant protein
Recombinant SARS-CoV-2 S Protein HR1 (N-6His-Sumo)
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Synonyms
COVID 19 S Protein HR1 (N-6His-Sumo) Coronavirus; Recombinant SARS-CoV-2 S Protein HR1 (N-6His-Sumo); 2019 Novel Coronavirus; Coronavirus; CoV; COVID-19 virus; HCoV-2; Human Coronavirus 2019; SARS2; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; S Protein HR1 (N-6His-Sumo); COVID-19 recombinant protein
Host
E Coli
Purity/Purification
Greater than 95% as determined by reducing SDS-PAGE.
Form/Format
Liquid. Supplied as a 0.2um filtered solution of PBS, pH7.4
Sequence
Gly910-Glu988
Tag
N-6His-Sumo
Species
SARS-CoV-2
Protein Construction
Recombinant 2019-nCoV S protein HR1 Protein is produced by our E Coli expression system and the target gene encoding Gly910-Glu988 is expressed with a 6His, Sumo tag at the N-terminus.
Preparation and Storage
Store at <-20 degree C, stable for 6 months. Please minimize freeze-thaw cycles.
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt; store it immediately at <-20 degree C.
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt; store it immediately at <-20 degree C.
Related Product Information for COVID-19 recombinant protein
The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion. After binding of RBD in S1 subunit of S protein on the virion to the ACE2 receptor on the target cell, the heptad repeat 1 (HR1) and 2 (HR2) domains in its S2 subunit of S protein interact with each other to form a six-helix bundle (6-HB) fusion core, bringing viral and cellular membranes into close proximity for fusion and infection. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
NCBI and Uniprot Product Information
UniProt Accession #
Molecular Weight
Mol_Mass: 47.9 kDa; AP_Mol_Mass: 50-60 kDa
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Product Notes
The COVID-19 (Catalog #AAA2567767) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Gly910-Glu 988 . It is sometimes possible for the material contained within the vial of "COVID 19 S Protein HR1 (N-6His-Sumo) Coronavirus, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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