Information
(Figure 1. Illustration of the replication-deficient MLV particle pseudotyped with SARS-CoV-2 Spike protein)
COVID 19 Pseudoviral Particles Omicron BA.2 Variant Coronavirus Pseudovirus | COVID-19 pseudovirus
SARS-CoV-2 Pseudoviral Particles, Omicron BA.2 Variant
Synonyms
COVID 19 Pseudoviral Particles Omicron BA.2 Variant Coronavirus; SARS-CoV-2 Pseudoviral Particles; Omicron BA.2 Variant; 2019 Novel Coronavirus; Coronavirus; CoV; COVID-19 virus; HCoV-2; Human Coronavirus 2019; SARS2; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Pseudoviral Particles Omicron BA.2 Variant; Omicron BA.2 Sub-Variant (B.1.1.529+BA*); COVID-19 pseudovirus
Form/Format
10 ml (2 tubes, 5 mL/tube), for 2 multi-well plates.
Application Notes
Our Pseudovirus Particles (PP) generate robust chemiluminescent signals in cell assays when coupled with our firefly luciferase assay kit (Catalog # MBS434279), useful for: 1) screening potential inhibitor to block SARS-CoV-2 entry and viral protein translation; 2) measuring the activity of and screening for neutralizing antibody against SARS-CoV-2-Omicron (refer to the Neutralization Assay Application Note).
Note
1. Amenable to HTS format (96-well, 384-well and 1536-well format).
2. HEK293-hACE2 stable cells are available seperately (Catalog #MBS434276, MBS434289)
2. HEK293-hACE2 stable cells are available seperately (Catalog #MBS434276, MBS434289)
Features
Robust: Excellent signal to noise (basal) ratio
Easy to use: Amenable to HTS format (96-well, 384-well and 1536-well format)
Easy to use: Amenable to HTS format (96-well, 384-well and 1536-well format)
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Upon receiving it, store at -70 degree C right away. Thaw* before immediate use.
Information
(Figure 1. Illustration of the replication-deficient MLV particle pseudotyped with SARS-CoV-2 Spike protein)
Information
(Figure 1. Illustration of the replication-deficient MLV particle pseudotyped with SARS-CoV-2 Spike protein)
Data
(Figure 2. Pseudoviral Particle (PP) Infection assays (SARS-CoV-2-Omicon BA2 variant pseudoviral particles on HEK293-ACE2 cells)A 384-well plate was used.Legends: SARS-2-CoV2-Omicron BA.2-PP: SARS-CoV-2 OmiBA2 variant MLV pseudovirus particles MBS434318(-): MLV control (w/o envelope spike protein) (Catalog # MBS434280))
Data
(Figure 2. Pseudoviral Particle (PP) Infection assays (SARS-CoV-2-Omicon BA2 variant pseudoviral particles on HEK293-ACE2 cells)A 384-well plate was used.Legends: SARS-2-CoV2-Omicron BA.2-PP: SARS-CoV-2 OmiBA2 variant MLV pseudovirus particles MBS434318(-): MLV control (w/o envelope spike protein) (Catalog # MBS434280))
Related Product Information for COVID-19 pseudovirus
SARS-CoV-2 Pseudoviral Particles, replication-deficient MLV pseudotyped with the SARS-CoV-2 spike protein (the Omicron BA.2 variant).
The SARS-CoV-2 Pseudoviral Particles are replication-deficient Maloneymurine leukemia virus (MLV or MuLV) pseudotyped with the SARS-CoV-2 spike protein carrying the Omircon BA.2 sub-variant genotype.
MLV-based virus system is a better choice than HIV-based lentivirus system for making pseudoviral particles in regards of lab safety and product quality. Gag-Pol is the only component from MLV.
Our Pseudovirus Particles generate robust chemiluminescent signals in cell assays when coupled with our firefly luciferase assay kit (Catalog #MBS434279), useful for 1) screening potential inhibitors to block SARS-CoV-2 entry and viral protein; 2) measuring the activity of and screening for neutralizing antibody against SARS-CoV-2.
The SARS-CoV-2 Pseudoviral Particles are replication-deficient Maloneymurine leukemia virus (MLV or MuLV) pseudotyped with the SARS-CoV-2 spike protein carrying the Omircon BA.2 sub-variant genotype.
MLV-based virus system is a better choice than HIV-based lentivirus system for making pseudoviral particles in regards of lab safety and product quality. Gag-Pol is the only component from MLV.
Our Pseudovirus Particles generate robust chemiluminescent signals in cell assays when coupled with our firefly luciferase assay kit (Catalog #MBS434279), useful for 1) screening potential inhibitors to block SARS-CoV-2 entry and viral protein; 2) measuring the activity of and screening for neutralizing antibody against SARS-CoV-2.
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Product Notes
The COVID-19 (Catalog #AAA434318) is a Pseudovirus and is intended for research purposes only. The product is available for immediate purchase. Our Pseudovirus Particles (PP) generate robust chemiluminescent signals in cell assays when coupled with our firefly luciferase assay kit (Catalog # MBS434279), useful for: 1) screening potential inhibitor to block SARS-CoV-2 entry and viral protein translation; 2) measuring the activity of and screening for neutralizing antibody against SARS-CoV-2-Omicron (refer to the Neutralization Assay Application Note). Researchers should empirically determine the suitability of the COVID-19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "COVID 19 Pseudoviral Particles Omicron BA.2 Variant Coronavirus, Pseudovirus" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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